4M6G

Structure of the Mycobacterium tuberculosis peptidoglycan amidase Rv3717 in complex with L-Alanine-iso-D-Glutamine reaction product

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008745	molecular_function	N-acetylmuramoyl-L-alanine amidase activity
A	0009253	biological_process	peptidoglycan catabolic process
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 401

Chain	Residue
A	HIS35
A	GLU70
A	HIS125
A	ALA403

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN A 402

Chain	Residue
A	HIS71

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site_id	AC3
Number of Residues	14
Details	BINDING SITE FOR L-ALANINE-ISO-D-GLUTAMINE

Chain	Residue
A	GLU70
A	VAL106
A	HIS125
A	LEU186
A	ALA187
A	GLY188
A	ZN401
A	HOH522
A	HOH512
A	HOH541
A	HIS35
A	LYS55
A	GLN58
A	ALA59

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:24019530

Chain	Residue	Details
A	GLU200

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:24019530, ECO:0000269|PubMed:24311595, ECO:0007744|PDB:4LQ6, ECO:0007744|PDB:4M6G, ECO:0007744|PDB:4M6I

Chain	Residue	Details
A	HIS35
A	GLU70
A	HIS125

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