Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 401 |
| Chain | Residue |
| A | ASP138 |
| A | GLU177 |
| A | ASP185 |
| A | GLU187 |
| A | GLU190 |
| A | HOH505 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 402 |
| Chain | Residue |
| A | GLU190 |
| A | HOH591 |
| A | HOH701 |
| A | GLU177 |
| A | ASN183 |
| A | ASP185 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 403 |
| Chain | Residue |
| A | ASP57 |
| A | ASP59 |
| A | GLN61 |
| A | HOH513 |
| A | HOH521 |
| A | HOH636 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 404 |
| Chain | Residue |
| A | TYR193 |
| A | THR194 |
| A | ILE197 |
| A | ASP200 |
| A | EDO416 |
| A | HOH552 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 405 |
| Chain | Residue |
| A | TYR211 |
| A | HOH832 |
| A | HOH925 |
| A | HOH926 |
| A | HOH927 |
| A | HOH928 |
| A | HOH931 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 406 |
| Chain | Residue |
| A | HIS142 |
| A | HIS146 |
| A | GLU166 |
| A | ASN420 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE H2S A 407 |
| Chain | Residue |
| A | GLN246 |
| A | HOH672 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE H2S A 408 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 409 |
| Chain | Residue |
| A | ASP43 |
| A | SER53 |
| A | LEU54 |
| A | TRP55 |
| A | ALA56 |
| A | LYS219 |
| A | HOH645 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 410 |
| Chain | Residue |
| A | LYS239 |
| A | HIS250 |
| A | HOH507 |
| A | HOH865 |
| A | HOH919 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 411 |
| Chain | Residue |
| A | TYR251 |
| A | HOH614 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 412 |
| Chain | Residue |
| A | TRP115 |
| A | ASP150 |
| A | TYR157 |
| A | EDO414 |
| A | ASN420 |
| A | HOH596 |
| A | HOH888 |
| A | HOH902 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 413 |
| Chain | Residue |
| A | ASN96 |
| A | ASP185 |
| A | GLU187 |
| A | GLU190 |
| A | GLY199 |
| A | HOH638 |
| A | HOH658 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 414 |
| Chain | Residue |
| A | TYR106 |
| A | TRP115 |
| A | ASN116 |
| A | EDO412 |
| A | ASN420 |
| A | HOH673 |
| A | HOH673 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 415 |
| Chain | Residue |
| A | HOH591 |
| A | HOH638 |
| site_id | BC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO A 416 |
| Chain | Residue |
| A | GLU190 |
| A | ASP191 |
| A | TYR193 |
| A | THR194 |
| A | PRO195 |
| A | ILE197 |
| A | CA404 |
| A | HOH552 |
| A | HOH858 |
| A | HOH924 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 417 |
| Chain | Residue |
| A | THR26 |
| A | ALA58 |
| A | TYR221 |
| A | THR222 |
| A | GLY223 |
| A | HOH775 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 418 |
| Chain | Residue |
| A | ASN112 |
| A | ALA113 |
| A | GLU143 |
| A | ARG203 |
| A | ASN420 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 419 |
| Chain | Residue |
| A | HOH704 |
| A | HOH738 |
| A | GLU160 |
| A | TYR221 |
| site_id | CC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ASN A 420 |
| Chain | Residue |
| A | ASN112 |
| A | ALA113 |
| A | PHE114 |
| A | TRP115 |
| A | HIS142 |
| A | GLU143 |
| A | HIS146 |
| A | TYR157 |
| A | GLU166 |
| A | HIS231 |
| A | ZN406 |
| A | EDO412 |
| A | EDO414 |
| A | EDO418 |
| A | HOH830 |
| A | HOH838 |
| A | HOH912 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VVAHELTHAV |
| Chain | Residue | Details |
| A | VAL139-VAL148 | |
