4M2A
Crystal structure of the udp-glucose pyrophosphorylase from Leishmania major in the post-reactive state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003983 | molecular_function | UTP:glucose-1-phosphate uridylyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005977 | biological_process | glycogen metabolic process |
| A | 0006011 | biological_process | UDP-glucose metabolic process |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0031981 | cellular_component | nuclear lumen |
| A | 0070569 | molecular_function | uridylyltransferase activity |
| A | 0097014 | cellular_component | ciliary plasm |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE UPG A 1001 |
| Chain | Residue |
| A | LEU81 |
| A | GLY220 |
| A | GLY256 |
| A | GLY257 |
| A | GLU284 |
| A | PHE305 |
| A | ASN306 |
| A | ASN308 |
| A | PHE376 |
| A | LYS380 |
| A | MG1002 |
| A | ASN82 |
| A | HOH2007 |
| A | HOH2064 |
| A | HOH2103 |
| A | HOH2240 |
| A | HOH2279 |
| A | HOH2498 |
| A | HOH2502 |
| A | HOH2503 |
| A | HOH2541 |
| A | HOH2548 |
| A | GLY83 |
| A | HOH2552 |
| A | HOH2585 |
| A | GLY84 |
| A | MET130 |
| A | GLN162 |
| A | GLY190 |
| A | HIS191 |
| A | ASN219 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 1002 |
| Chain | Residue |
| A | GLY84 |
| A | UPG1001 |
| A | SO41003 |
| A | HOH2549 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1003 |
| Chain | Residue |
| A | GLY84 |
| A | LEU85 |
| A | GLY86 |
| A | THR87 |
| A | MG1002 |
| A | HOH2547 |
