4M1E
Crystal structure of purine nucleoside phosphorylase I from Planctomyces limnophilus DSM 3776, NYSGRC Target 029364.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0016763 | molecular_function | pentosyltransferase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0016763 | molecular_function | pentosyltransferase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| C | 0009116 | biological_process | nucleoside metabolic process |
| C | 0016757 | molecular_function | glycosyltransferase activity |
| C | 0016763 | molecular_function | pentosyltransferase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| D | 0009116 | biological_process | nucleoside metabolic process |
| D | 0016757 | molecular_function | glycosyltransferase activity |
| D | 0016763 | molecular_function | pentosyltransferase activity |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| E | 0009116 | biological_process | nucleoside metabolic process |
| E | 0016757 | molecular_function | glycosyltransferase activity |
| E | 0016763 | molecular_function | pentosyltransferase activity |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| F | 0009116 | biological_process | nucleoside metabolic process |
| F | 0016757 | molecular_function | glycosyltransferase activity |
| F | 0016763 | molecular_function | pentosyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 400 |
| Chain | Residue |
| A | GLY30 |
| A | THR31 |
| A | HIS62 |
| A | ARG82 |
| A | HIS84 |
| A | ASN113 |
| A | ALA114 |
| A | SER213 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ADE A 401 |
| Chain | Residue |
| A | ALA115 |
| A | GLY116 |
| A | LEU193 |
| A | GLU194 |
| A | TYR199 |
| A | VAL210 |
| A | GLY211 |
| A | MSE212 |
| A | THR235 |
| A | ASP236 |
| A | CYS238 |
| A | HOH508 |
| A | ALA114 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 6PC A 402 |
| Chain | Residue |
| A | ARG170 |
| A | PRO181 |
| A | LYS182 |
| A | HOH520 |
| F | ASN119 |
| F | GLN121 |
| F | HIS179 |
| F | PRO181 |
| F | 6PC402 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 400 |
| Chain | Residue |
| B | GLY30 |
| B | THR31 |
| B | HIS62 |
| B | ARG82 |
| B | HIS84 |
| B | ASN113 |
| B | ALA114 |
| B | SER213 |
| B | HOH512 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ADE B 401 |
| Chain | Residue |
| B | ALA114 |
| B | ALA115 |
| B | GLY116 |
| B | LEU193 |
| B | GLU194 |
| B | TYR199 |
| B | VAL210 |
| B | GLY211 |
| B | MSE212 |
| B | THR235 |
| B | ASP236 |
| B | CYS238 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 6PC B 402 |
| Chain | Residue |
| B | ARG170 |
| B | PRO181 |
| B | LYS182 |
| E | ASN119 |
| E | GLN121 |
| E | LEU122 |
| E | HIS179 |
| E | PRO181 |
| E | 6PC402 |
| E | HOH556 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 400 |
| Chain | Residue |
| C | GLY30 |
| C | THR31 |
| C | HIS62 |
| C | ARG82 |
| C | HIS84 |
| C | ASN113 |
| C | ALA114 |
| C | SER213 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE ADE C 401 |
| Chain | Residue |
| C | ALA115 |
| C | GLY116 |
| C | LEU193 |
| C | GLU194 |
| C | TYR199 |
| C | GLY211 |
| C | MSE212 |
| C | THR235 |
| C | ASP236 |
| C | CYS238 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 6PC C 402 |
| Chain | Residue |
| C | ASN119 |
| C | GLN121 |
| C | LEU122 |
| C | HIS179 |
| C | PRO181 |
| C | HOH573 |
| D | ARG170 |
| D | PRO181 |
| D | LYS182 |
| D | 6PC301 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 E 400 |
| Chain | Residue |
| E | GLY30 |
| E | THR31 |
| E | HIS62 |
| E | ARG82 |
| E | HIS84 |
| E | ASN113 |
| E | ALA114 |
| E | SER213 |
| site_id | BC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ADE E 401 |
| Chain | Residue |
| E | GLY116 |
| E | LEU193 |
| E | GLU194 |
| E | TYR199 |
| E | VAL210 |
| E | GLY211 |
| E | MSE212 |
| E | THR235 |
| E | ASP236 |
| E | CYS238 |
| E | ALA114 |
| E | ALA115 |
| site_id | BC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 6PC E 402 |
| Chain | Residue |
| B | ASN119 |
| B | GLN121 |
| B | HIS179 |
| B | PRO181 |
| B | 6PC402 |
| E | ARG170 |
| E | PRO181 |
| E | LYS182 |
| E | HOH556 |
| site_id | BC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 6PC D 301 |
| Chain | Residue |
| C | ARG170 |
| C | PRO181 |
| C | LYS182 |
| C | 6PC402 |
| C | HOH573 |
| D | ASN119 |
| D | GLN121 |
| D | LEU122 |
| D | HIS179 |
| D | PRO181 |
| site_id | BC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 D 302 |
| Chain | Residue |
| D | GLY30 |
| D | THR31 |
| D | HIS62 |
| D | ARG82 |
| D | HIS84 |
| D | ASN113 |
| D | ALA114 |
| D | SER213 |
| D | HOH419 |
| D | HOH470 |
| site_id | BC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ADE D 303 |
| Chain | Residue |
| D | ALA114 |
| D | ALA115 |
| D | GLY116 |
| D | LEU193 |
| D | GLU194 |
| D | TYR199 |
| D | VAL210 |
| D | GLY211 |
| D | MSE212 |
| D | THR235 |
| D | ASP236 |
| D | CYS238 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 F 400 |
| Chain | Residue |
| F | GLY30 |
| F | THR31 |
| F | ARG82 |
| F | HIS84 |
| F | ASN113 |
| F | ALA114 |
| F | SER213 |
| site_id | BC8 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ADE F 401 |
| Chain | Residue |
| F | ALA114 |
| F | ALA115 |
| F | GLY116 |
| F | LEU193 |
| F | GLU194 |
| F | TYR199 |
| F | VAL210 |
| F | GLY211 |
| F | MSE212 |
| F | THR235 |
| F | ASP236 |
| F | CYS238 |
| F | HOH599 |
| site_id | BC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 6PC F 402 |
| Chain | Residue |
| A | ASN119 |
| A | GLN121 |
| A | LEU122 |
| A | HIS179 |
| A | PRO181 |
| A | 6PC402 |
| A | HOH514 |
| F | ARG170 |
| F | PRO181 |
| F | LYS182 |
Functional Information from PROSITE/UniProt
| site_id | PS01240 |
| Number of Residues | 42 |
| Details | PNP_MTAP_2 Purine and other phosphorylases family 2 signature. VameGrfHyYegysLeqvTfpVrVmkamGvkt.LLvtNAaGGI |
| Chain | Residue | Details |
| A | VAL77-ILE118 |
