4M0K

Crystal structure of adenine phosphoribosyltransferase from Rhodothermus marinus DSM 4252, NYSGRC Target 029775.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0002055	molecular_function	adenine binding
A	0003999	molecular_function	adenine phosphoribosyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0006166	biological_process	purine ribonucleoside salvage
A	0006168	biological_process	adenine salvage
A	0016208	molecular_function	AMP binding
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0044209	biological_process	AMP salvage
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0002055	molecular_function	adenine binding
B	0003999	molecular_function	adenine phosphoribosyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0006166	biological_process	purine ribonucleoside salvage
B	0006168	biological_process	adenine salvage
B	0016208	molecular_function	AMP binding
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0044209	biological_process	AMP salvage
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0002055	molecular_function	adenine binding
C	0003999	molecular_function	adenine phosphoribosyltransferase activity
C	0005737	cellular_component	cytoplasm
C	0006166	biological_process	purine ribonucleoside salvage
C	0006168	biological_process	adenine salvage
C	0016208	molecular_function	AMP binding
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0044209	biological_process	AMP salvage
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0002055	molecular_function	adenine binding
D	0003999	molecular_function	adenine phosphoribosyltransferase activity
D	0005737	cellular_component	cytoplasm
D	0006166	biological_process	purine ribonucleoside salvage
D	0006168	biological_process	adenine salvage
D	0016208	molecular_function	AMP binding
D	0016740	molecular_function	transferase activity
D	0016757	molecular_function	glycosyltransferase activity
D	0044209	biological_process	AMP salvage
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE AMP A 300

Chain	Residue
A	GLN25
A	GLY130
A	GLY131
A	THR132
A	LEU156
A	HOH415
A	HOH421
A	HOH426
A	HOH427
A	HOH444
A	HOH490
A	PHE26
A	HOH555
A	LYS27
A	GLU62
A	ASP124
A	ASP125
A	VAL126
A	ALA128
A	THR129

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 301

Chain	Residue
A	ASP77
A	HOH472
A	HOH474
A	HOH521
A	HOH522

---

site_id	AC3
Number of Residues	20
Details	BINDING SITE FOR RESIDUE AMP B 300

Chain	Residue
B	GLN25
B	PHE26
B	LYS27
B	ASP124
B	ASP125
B	VAL126
B	ALA128
B	THR129
B	GLY130
B	GLY131
B	THR132
B	LEU156
B	HOH402
B	HOH407
B	HOH416
B	HOH417
B	HOH451
B	HOH480
B	HOH488
B	HOH490

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 301

Chain	Residue
B	HOH456
B	HOH466
B	HOH478
B	HOH495
B	HOH544
B	HOH548

---

site_id	AC5
Number of Residues	20
Details	BINDING SITE FOR RESIDUE AMP C 201

Chain	Residue
C	GLN25
C	PHE26
C	LYS27
C	ASP124
C	ASP125
C	VAL126
C	ALA128
C	THR129
C	GLY130
C	GLY131
C	THR132
C	LEU156
C	HOH303
C	HOH311
C	HOH315
C	HOH316
C	HOH391
C	HOH398
C	HOH404
C	HOH469

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 202

Chain	Residue
B	GLN11
B	HOH409
B	HOH437
C	GLU134
C	HOH331
C	HOH368

---

site_id	AC7
Number of Residues	20
Details	BINDING SITE FOR RESIDUE AMP D 300

Chain	Residue
D	GLN25
D	PHE26
D	LYS27
D	ASP124
D	ASP125
D	VAL126
D	ALA128
D	THR129
D	GLY130
D	GLY131
D	THR132
D	LEU156
D	HOH412
D	HOH419
D	HOH440
D	HOH475
D	HOH482
D	HOH489
D	HOH503
D	HOH529

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA D 301

Chain	Residue
D	HOH427
D	HOH464
D	HOH496
D	HOH498
A	GLU134
D	GLN11

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