4M06

Crystal Structure of Mutant Chlorite Dismutase from Candidatus Nitrospira defluvii W145F in Complex with Cyanide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
A	0020037	molecular_function	heme binding
A	0046872	molecular_function	metal ion binding
A	0050587	molecular_function	chlorite O2-lyase activity
B	0016491	molecular_function	oxidoreductase activity
B	0020037	molecular_function	heme binding
B	0046872	molecular_function	metal ion binding
B	0050587	molecular_function	chlorite O2-lyase activity
C	0016491	molecular_function	oxidoreductase activity
C	0020037	molecular_function	heme binding
C	0046872	molecular_function	metal ion binding
C	0050587	molecular_function	chlorite O2-lyase activity
D	0016491	molecular_function	oxidoreductase activity
D	0020037	molecular_function	heme binding
D	0046872	molecular_function	metal ion binding
D	0050587	molecular_function	chlorite O2-lyase activity
E	0016491	molecular_function	oxidoreductase activity
E	0020037	molecular_function	heme binding
E	0046872	molecular_function	metal ion binding
E	0050587	molecular_function	chlorite O2-lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM A 301

Chain	Residue
A	PRO108
A	ALA164
A	LEU168
A	ARG173
A	LEU175
A	PHE186
A	THR188
A	PHE190
A	LEU201
A	LEU205
A	PHE217
A	THR109
A	CYN303
A	TYR110
A	VAL111
A	ILE139
A	PHE145
A	MET157
A	HIS160
A	THR161

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 302

Chain	Residue
A	LYS140
C	ARG215
C	ARG216
C	PHE217
C	HIS219

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CYN A 303

Chain	Residue
A	LEU175
A	HEM301

---

site_id	AC4
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM B 301

Chain	Residue
B	PRO108
B	THR109
B	TYR110
B	LEU122
B	ILE137
B	ILE139
B	PHE145
B	MET157
B	HIS160
B	THR161
B	ALA164
B	LEU168
B	ARG173
B	LEU175
B	PHE186
B	THR188
B	PHE190
B	LEU205
B	PHE217
B	CYN302

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CYN B 302

Chain	Residue
B	LEU175
B	HEM301

---

site_id	AC6
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM C 301

Chain	Residue
C	PRO108
C	THR109
C	TYR110
C	VAL111
C	ILE139
C	HIS160
C	THR161
C	ALA164
C	LEU168
C	ARG173
C	LEU175
C	PHE186
C	THR188
C	PHE190
C	LEU201
C	LEU205
C	PHE217
C	CYN302
C	HOH403

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CYN C 302

Chain	Residue
C	HEM301

---

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO C 303

Chain	Residue
C	ARG173

---

site_id	AC9
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEM D 301

Chain	Residue
D	PRO108
D	THR109
D	TYR110
D	VAL111
D	ILE139
D	PHE145
D	MET157
D	HIS160
D	THR161
D	ALA164
D	ARG173
D	PHE186
D	THR188
D	PHE190
D	LEU205
D	PHE217
D	CYN302

---

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CYN D 302

Chain	Residue
D	HEM301

---

site_id	BC2
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM E 301

Chain	Residue
E	ALA164
E	LEU168
E	ARG173
E	LEU175
E	PHE186
E	PHE190
E	LEU205
E	PHE217
E	CYN302
E	PRO108
E	THR109
E	TYR110
E	VAL111
E	LEU122
E	ILE137
E	ILE139
E	PHE145
E	MET157
E	HIS160
E	THR161

---

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CYN E 302

Chain	Residue
E	HEM301

---

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO E 303

Chain	Residue
D	LEU100
D	LEU181
E	LEU61
E	SER62
E	ASP63
E	THR221

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