4LW3

Crystal structure of the Drosophila beta1,4galactosyltransferase7 catalytic domain D211N single mutant enzyme complex with manganese and UDP-galactose

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005975	biological_process	carbohydrate metabolic process
A	0016757	molecular_function	glycosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 401

Chain	Residue
A	ASP147
A	HIS241
A	HIS243
A	GDU402
A	HOH504

---

site_id	AC2
Number of Residues	27
Details	BINDING SITE FOR RESIDUE GDU A 402

Chain	Residue
A	PHE121
A	ARG123
A	ASP145
A	VAL146
A	ASP147
A	TYR177
A	GLY185
A	TRP207
A	GLY208
A	GLU210
A	ASN211
A	HIS241
A	HIS243
A	ARG250
A	MN401
A	HOH511
A	HOH516
A	HOH528
A	HOH540
A	HOH579
A	HOH580
A	HOH591
A	HOH595
A	PRO82
A	PHE83
A	ARG84
A	ARG86

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24052259","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20236943","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3LW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M4K","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24052259","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4LW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M4K","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20236943","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24052259","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3LW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M4K","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20236943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4LW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M4K","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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