4LW1
Fragment-Based Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 1XS A 201 |
| Chain | Residue |
| A | ARG41 |
| A | MET57 |
| A | ALA59 |
| A | THR60 |
| A | ASN85 |
| A | VAL93 |
| A | ILE95 |
| A | HOH313 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 1XS A 202 |
| Chain | Residue |
| A | ILE33 |
| A | ARG43 |
| A | SER55 |
| A | LEU87 |
| A | ARG91 |
| A | VAL93 |
| A | ARG31 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"26474068","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
