Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4LSE

Ion selectivity of OmpF porin soaked in 0.2M NaBr

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001530	molecular_function	lipopolysaccharide binding
A	0005216	molecular_function	monoatomic ion channel activity
A	0005515	molecular_function	protein binding
A	0006811	biological_process	monoatomic ion transport
A	0008289	molecular_function	lipid binding
A	0009279	cellular_component	cell outer membrane
A	0015031	biological_process	protein transport
A	0015288	molecular_function	porin activity
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0034702	cellular_component	monoatomic ion channel complex
A	0042802	molecular_function	identical protein binding
A	0042912	molecular_function	colicin transmembrane transporter activity
A	0043213	biological_process	bacteriocin transport
A	0046930	cellular_component	pore complex
A	0070207	biological_process	protein homotrimerization
A	0097718	molecular_function	disordered domain specific binding
B	0001530	molecular_function	lipopolysaccharide binding
B	0005216	molecular_function	monoatomic ion channel activity
B	0005515	molecular_function	protein binding
B	0006811	biological_process	monoatomic ion transport
B	0008289	molecular_function	lipid binding
B	0009279	cellular_component	cell outer membrane
B	0015031	biological_process	protein transport
B	0015288	molecular_function	porin activity
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0034702	cellular_component	monoatomic ion channel complex
B	0042802	molecular_function	identical protein binding
B	0042912	molecular_function	colicin transmembrane transporter activity
B	0043213	biological_process	bacteriocin transport
B	0046930	cellular_component	pore complex
B	0070207	biological_process	protein homotrimerization
B	0097718	molecular_function	disordered domain specific binding
C	0001530	molecular_function	lipopolysaccharide binding
C	0005216	molecular_function	monoatomic ion channel activity
C	0005515	molecular_function	protein binding
C	0006811	biological_process	monoatomic ion transport
C	0008289	molecular_function	lipid binding
C	0009279	cellular_component	cell outer membrane
C	0015031	biological_process	protein transport
C	0015288	molecular_function	porin activity
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0034702	cellular_component	monoatomic ion channel complex
C	0042802	molecular_function	identical protein binding
C	0042912	molecular_function	colicin transmembrane transporter activity
C	0043213	biological_process	bacteriocin transport
C	0046930	cellular_component	pore complex
C	0070207	biological_process	protein homotrimerization
C	0097718	molecular_function	disordered domain specific binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR A 401

Chain	Residue
A	LYS16

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR A 402

Chain	Residue
A	GLN66
A	ASN68
A	HOH582
A	HOH607

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 403

Chain	Residue
A	SER125
A	ARG167

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 404

Chain	Residue
A	TYR40
A	MET38
A	THR39

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG A 405

Chain	Residue
A	HOH696

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 406

Chain	Residue
A	ASN207
A	ASN236
A	ASN252

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PEG A 407

Chain	Residue
A	TYR32
A	HOH696

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE C8E A 408

Chain	Residue
A	ALA228
A	ALA261

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BR B 401

Chain	Residue
A	ASP126
A	ARG168
B	SER70
B	GLU71
B	GLY72

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR B 402

Chain	Residue
B	LYS16
B	HOH516

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG B 403

Chain	Residue
B	PEG404

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PEG B 404

Chain	Residue
B	TYR32
B	ASP121
B	MG403

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE C8E B 405

Chain	Residue
B	VAL174

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR B 406

Chain	Residue
B	PHE45
C	LYS16
C	ALA17
C	ARG42

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 407

Chain	Residue
B	ASN207
B	ASN236
B	ASN252
B	HOH572
B	HOH609
B	HOH622

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 401

Chain	Residue
C	ASN207
C	ASN236
C	ASN252
C	HOH617
C	HOH625

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 403

Chain	Residue
C	ARG168
C	ASN170
C	HOH703
C	HOH704

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PEG C 404

Chain	Residue
C	ALA166
C	ARG167
C	SER248
C	GLY249

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PEG C 405

Chain	Residue
C	TYR22
C	GLU117
C	HOH706

Functional Information from PROSITE/UniProt

site_id	PS00576
Number of Residues	17
Details	GRAM_NEG_PORIN General diffusion Gram-negative porins signature. FevGatYyFnKnmSTYV

Chain	Residue	Details
A	PHE295-VAL311

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	510
Details	TRANSMEM: Beta stranded

Chain	Residue	Details
A	ALA1-LYS6
A	GLY8-PHE23
A	THR39-ILE51
A	ASP54-GLN66
A	LEU83-ALA91
A	GLY94-ARG100
A	GLY135-ASN141
A	GLY150-GLY159
A	ASP172-TYR182
A	GLY184-ASP195
A	ALA211-ALA222
A	ASN224-ARG235
A	LYS253-PHE265
A	GLY268-LYS281
A	VAL292-PHE303
A	ASN306-ILE315
A	THR331-PHE340
B	ALA1-LYS6
B	GLY8-PHE23
B	THR39-ILE51
B	ASP54-GLN66
B	LEU83-ALA91
B	GLY94-ARG100
B	GLY135-ASN141
B	GLY150-GLY159
B	ASP172-TYR182
B	GLY184-ASP195
B	ALA211-ALA222
B	ASN224-ARG235
B	LYS253-PHE265
B	GLY268-LYS281
B	VAL292-PHE303
B	ASN306-ILE315
B	THR331-PHE340
C	ALA1-LYS6
C	GLY8-PHE23
C	THR39-ILE51
C	ASP54-GLN66
C	LEU83-ALA91
C	GLY94-ARG100
C	GLY135-ASN141
C	GLY150-GLY159
C	ASP172-TYR182
C	GLY184-ASP195
C	ALA211-ALA222
C	ASN224-ARG235
C	LYS253-PHE265
C	GLY268-LYS281
C	VAL292-PHE303
C	ASN306-ILE315
C	THR331-PHE340

site_id	SWS_FT_FI2
Number of Residues	42
Details	TOPO_DOM: Periplasmic

Chain	Residue	Details
A	ASN52-SER53
A	ASP92-VAL93
A	SER142-ASP149
A	ASP266-PHE267
A	ASN304-LYS305
B	ASN52-SER53
B	ASP92-VAL93
B	SER142-ASP149
B	ASP266-PHE267
B	ASN304-LYS305
C	ASN52-SER53
C	ASP92-VAL93
C	SER142-ASP149
C	ASP266-PHE267
C	ASN304-LYS305
A	ASP7
A	GLU183
A	ASN223
B	ASP7
B	GLU183
B	ASN223
C	ASP7
C	GLU183
C	ASN223

site_id	SWS_FT_FI3
Number of Residues	378
Details	TOPO_DOM: Extracellular

Chain	Residue	Details
A	SER24-MET38
A	GLY67-ARG82
A	ASN101-GLY134
A	LYS160-GLY171
A	ARG196-LYS210
A	ASN236-ASN252
A	ASP282-LEU291
A	ASN316-ASP330
B	SER24-MET38
B	GLY67-ARG82
B	ASN101-GLY134
B	LYS160-GLY171
B	ARG196-LYS210
B	ASN236-ASN252
B	ASP282-LEU291
B	ASN316-ASP330
C	SER24-MET38
C	GLY67-ARG82
C	ASN101-GLY134
C	LYS160-GLY171
C	ARG196-LYS210
C	ASN236-ASN252
C	ASP282-LEU291
C	ASN316-ASP330

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)