4LS5
Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Bacillus subtilis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K A 501 |
| Chain | Residue |
| A | ASN300 |
| A | ALA301 |
| A | GLU348 |
| A | SER393 |
| A | ASN394 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K A 502 |
| Chain | Residue |
| A | HOH799 |
| A | LYS206 |
| A | LEU208 |
| A | ASP226 |
| A | HOH729 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 503 |
| Chain | Residue |
| A | ASP21 |
| A | ARG128 |
| A | TYR253 |
| A | LEU354 |
| A | GLU358 |
| A | HOH857 |
| A | HOH893 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 504 |
| Chain | Residue |
| A | ALA67 |
| A | ARG68 |
| A | GLN75 |
| A | HOH701 |
| A | HOH811 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K B 501 |
| Chain | Residue |
| B | ASN300 |
| B | ALA301 |
| B | GLU348 |
| B | SER393 |
| B | ASN394 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K B 502 |
| Chain | Residue |
| A | ASP55 |
| B | LYS206 |
| B | LEU208 |
| B | ASP226 |
| B | HOH646 |
| B | HOH778 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 503 |
| Chain | Residue |
| A | ASP60 |
| A | TYR61 |
| A | HOH814 |
| B | THR210 |
| B | ASN211 |
| B | HOH860 |
| B | HOH863 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 504 |
| Chain | Residue |
| A | PRO131 |
| B | ASN205 |
| B | HIS267 |
| B | ILE268 |
| B | THR269 |
| B | HOH912 |
Functional Information from PROSITE/UniProt
| site_id | PS00606 |
| Number of Residues | 17 |
| Details | KS3_1 Ketosynthase family 3 (KS3) active site signature. GVNscTVtACATGtnSI |
| Chain | Residue | Details |
| A | GLY154-ILE170 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: For beta-ketoacyl synthase activity => ECO:0000255|PROSITE-ProRule:PRU01348 |
| Chain | Residue | Details |
| A | CYS163 | |
| A | HIS302 | |
| A | HIS339 | |
| B | CYS163 | |
| B | HIS302 | |
| B | HIS339 |
