4LRY
Crystal Structure of the E.coli DhaR(N)-DhaK(T79L) complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004371 | molecular_function | glycerone kinase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006071 | biological_process | glycerol metabolic process |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019563 | biological_process | glycerol catabolic process |
| A | 0042182 | biological_process | ketone catabolic process |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0046365 | biological_process | monosaccharide catabolic process |
| A | 0046835 | biological_process | carbohydrate phosphorylation |
| A | 0047324 | molecular_function | phosphoenolpyruvate-glycerone phosphotransferase activity |
| A | 0061610 | biological_process | glycerol to glycerone phosphate metabolic process |
| A | 1990234 | cellular_component | transferase complex |
| B | 0004371 | molecular_function | glycerone kinase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006071 | biological_process | glycerol metabolic process |
| B | 0006974 | biological_process | DNA damage response |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019563 | biological_process | glycerol catabolic process |
| B | 0042182 | biological_process | ketone catabolic process |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0046365 | biological_process | monosaccharide catabolic process |
| B | 0046835 | biological_process | carbohydrate phosphorylation |
| B | 0047324 | molecular_function | phosphoenolpyruvate-glycerone phosphotransferase activity |
| B | 0061610 | biological_process | glycerol to glycerone phosphate metabolic process |
| B | 1990234 | cellular_component | transferase complex |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 401 |
| Chain | Residue |
| A | GLY52 |
| A | GLY53 |
| A | HIS56 |
| A | SER80 |
| A | LYS104 |
| A | ASP109 |
| A | HIS218 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 401 |
| Chain | Residue |
| B | HIS56 |
| B | SER80 |
| B | LYS104 |
| B | TYR106 |
| B | ASP109 |
| B | HIS218 |
| B | GLY52 |
| B | GLY53 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 690 |
| Details | Domain: {"description":"DhaK","evidences":[{"source":"PROSITE-ProRule","id":"PRU00814","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"21209328","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Tele-hemiaminal-histidine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00814","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12813127","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15476397","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21209328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OI2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UOD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UOE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PNK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PNL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PNQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12813127","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15476397","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21209328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OI2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UOD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UOE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PNK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PNL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PNQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12813127","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21209328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OI2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PNK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PNL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PNQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 274 |
| Details | Domain: {"description":"GAF","evidences":[{"source":"PubMed","id":"24440518","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 124 |
| Details | Domain: {"description":"PAS","evidences":[{"source":"PubMed","id":"24440518","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
