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4LRU

Crystal structure of glyoxalase III (Orf 19.251) from Candida albicans

Functional Information from GO Data
ChainGOidnamespacecontents
A0005737cellular_componentcytoplasm
A0006508biological_processproteolysis
A0016829molecular_functionlyase activity
A0019172molecular_functionglyoxalase III activity
A0019243biological_processmethylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
A0019249biological_processlactate biosynthetic process
A0030445cellular_componentyeast-form cell wall
A0030446cellular_componenthyphal cell wall
A0034727biological_processpiecemeal microautophagy of the nucleus
A0045454biological_processcell redox homeostasis
A0062040cellular_componentfungal biofilm matrix
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 301
ChainResidue
AGLU34
ALYS38
ATHR150
AGLU152
AHOH483
AHOH566

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ACT A 302
ChainResidue
AHOH444
AVAL59
ALYS69
AASP73

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsACT_SITE: ACT_SITE => ECO:0000305|PubMed:24302734
ChainResidueDetails
ACYS136
AHIS137
AGLU168

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Cysteine sulfinic acid (-SO2H) => ECO:0000250|UniProtKB:Q04432
ChainResidueDetails
ACYS136

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PDB entries from 2024-10-16

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