Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A 401 |
Chain | Residue |
A | GLY78 |
A | SER79 |
A | SER108 |
A | SER109 |
A | SER110 |
A | HOH582 |
A | HOH687 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A 402 |
Chain | Residue |
A | GLY177 |
A | HOH597 |
A | HOH697 |
A | HOH744 |
A | HOH789 |
A | TYR85 |
A | THR176 |
site_id | AC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 A 403 |
Chain | Residue |
A | GLY68 |
A | SER178 |
A | THR180 |
A | SER282 |
A | GOL406 |
A | HOH521 |
A | HOH742 |
A | HOH777 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL A 404 |
Chain | Residue |
A | SER236 |
A | GLY237 |
A | ALA238 |
A | HOH570 |
site_id | AC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE GOL A 405 |
Chain | Residue |
A | THR-1 |
A | SER-2 |
A | HOH702 |
site_id | AC6 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 406 |
Chain | Residue |
A | GLY68 |
A | THR70 |
A | GLY177 |
A | SER178 |
A | SO4403 |
A | HOH814 |
A | HOH815 |
site_id | AC7 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL A 407 |
Chain | Residue |
A | VAL267 |
A | PRO269 |
A | TYR272 |
A | ALA309 |
A | SER325 |
A | LYS326 |
A | HOH526 |
A | HOH678 |
site_id | AC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL A 408 |
Chain | Residue |
A | ALA183 |
A | TRP192 |
A | THR193 |
A | ASP211 |
site_id | AC9 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE GOL A 409 |
site_id | BC1 |
Number of Residues | 29 |
Details | BINDING SITE FOR CHAIN I OF SER-LEU-PHE-HIS-PHENYLALANYL-REDUCED-PEPTIDE-BOND-TYROSYL- THR-PRO |
Chain | Residue |
A | ASP12 |
A | ASP30 |
A | ASP32 |
A | GLY34 |
A | ILE73 |
A | SER74 |
A | TYR75 |
A | GLY76 |
A | ASP77 |
A | PHE111 |
A | ASP114 |
A | ILE117 |
A | PHE189 |
A | ASP215 |
A | GLY217 |
A | THR218 |
A | THR219 |
A | TYR222 |
A | PHE284 |
A | ILE297 |
A | ILE301 |
A | HOH509 |
A | HOH811 |
I | HOH501 |
I | HOH502 |
I | HOH503 |
I | HOH504 |
I | HOH505 |
I | HOH506 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
Chain | Residue | Details |
A | LEU29-VAL40 | |
A | GLY212-LEU223 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: |
Chain | Residue | Details |
A | ASP32 | |
A | SER194 | |