4LMG
Crystal structure of AFT2 in complex with DNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| A | 0010106 | biological_process | cellular response to iron ion starvation |
| A | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| B | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| B | 0010106 | biological_process | cellular response to iron ion starvation |
| B | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| C | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| C | 0010106 | biological_process | cellular response to iron ion starvation |
| C | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| D | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| D | 0010106 | biological_process | cellular response to iron ion starvation |
| D | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 201 |
| Chain | Residue |
| A | CYS86 |
| A | CYS109 |
| A | HIS133 |
| A | HIS135 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 201 |
| Chain | Residue |
| B | CYS86 |
| B | CYS109 |
| B | HIS133 |
| B | HIS135 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 202 |
| Chain | Residue |
| B | HIS55 |
| B | HOH301 |
| B | ASP53 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 201 |
| Chain | Residue |
| C | CYS86 |
| C | CYS109 |
| C | HIS133 |
| C | HIS135 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 201 |
| Chain | Residue |
| D | CYS86 |
| D | CYS109 |
| D | HIS133 |
| D | HIS135 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 202 |
| Chain | Residue |
| D | ASP53 |
| D | HIS55 |
| D | HOH301 |
| D | HOH302 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 76 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:24591629, ECO:0007744|PDB:4LMG |
| Chain | Residue | Details |
| A | ASP53 | |
| A | LYS81 | |
| A | CYS86 | |
| A | SER88 | |
| A | CYS109 | |
| A | VAL119 | |
| A | ARG120 | |
| A | HIS133 | |
| A | HIS135 | |
| A | GLN157 | |
| A | ASN159 | |
| A | ARG54 | |
| B | ASP53 | |
| B | ARG54 | |
| B | HIS55 | |
| B | LYS58 | |
| B | ILE74 | |
| B | GLU75 | |
| B | ARG76 | |
| B | SER77 | |
| B | ASP78 | |
| B | LYS81 | |
| A | HIS55 | |
| B | CYS86 | |
| B | SER88 | |
| B | CYS109 | |
| B | VAL119 | |
| B | ARG120 | |
| B | HIS133 | |
| B | HIS135 | |
| B | GLN157 | |
| B | ASN159 | |
| C | ASP53 | |
| A | LYS58 | |
| C | ARG54 | |
| C | HIS55 | |
| C | LYS58 | |
| C | ILE74 | |
| C | GLU75 | |
| C | ARG76 | |
| C | SER77 | |
| C | ASP78 | |
| C | LYS81 | |
| C | CYS86 | |
| A | ILE74 | |
| C | SER88 | |
| C | CYS109 | |
| C | VAL119 | |
| C | ARG120 | |
| C | HIS133 | |
| C | HIS135 | |
| C | GLN157 | |
| C | ASN159 | |
| D | ASP53 | |
| D | ARG54 | |
| A | GLU75 | |
| D | HIS55 | |
| D | LYS58 | |
| D | ILE74 | |
| D | GLU75 | |
| D | ARG76 | |
| D | SER77 | |
| D | ASP78 | |
| D | LYS81 | |
| D | CYS86 | |
| D | SER88 | |
| A | ARG76 | |
| D | CYS109 | |
| D | VAL119 | |
| D | ARG120 | |
| D | HIS133 | |
| D | HIS135 | |
| D | GLN157 | |
| D | ASN159 | |
| A | SER77 | |
| A | ASP78 |
