Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEC A 801 |
| Chain | Residue |
| A | VAL185 |
| A | LYS244 |
| A | ALA249 |
| A | GLY570 |
| A | HEC802 |
| A | HOH961 |
| A | HOH983 |
| A | HOH1170 |
| A | HOH1562 |
| A | CYS186 |
| A | CYS189 |
| A | HIS190 |
| A | ILE196 |
| A | ILE229 |
| A | VAL232 |
| A | HIS233 |
| A | TRP239 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEC A 802 |
| Chain | Residue |
| A | LYS86 |
| A | ILE196 |
| A | TYR197 |
| A | HIS198 |
| A | GLN199 |
| A | ALA200 |
| A | THR205 |
| A | CYS206 |
| A | CYS209 |
| A | HIS210 |
| A | PHE214 |
| A | ARG218 |
| A | LYS220 |
| A | HIS222 |
| A | LEU228 |
| A | TRP239 |
| A | GLY240 |
| A | GLU630 |
| A | HEC801 |
| A | HOH1005 |
| A | HOH1035 |
| A | HOH1441 |
| A | HOH1809 |
| site_id | AC3 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEC A 803 |
| Chain | Residue |
| A | SER102 |
| A | ILE180 |
| A | VAL181 |
| A | SER226 |
| A | ILE229 |
| A | HIS230 |
| A | HIS233 |
| A | VAL253 |
| A | ASP255 |
| A | CYS257 |
| A | CYS260 |
| A | HIS261 |
| A | ASN272 |
| A | TRP273 |
| A | ILE276 |
| A | VAL281 |
| A | HIS319 |
| A | HEC804 |
| A | HOH905 |
| A | HOH929 |
| A | HOH953 |
| A | HOH981 |
| A | HOH1077 |
| A | HOH1797 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE HEC A 804 |
| Chain | Residue |
| A | ASP255 |
| A | CYS282 |
| A | SER284 |
| A | CYS285 |
| A | HIS286 |
| A | LEU318 |
| A | HIS319 |
| A | LYS322 |
| A | HEC803 |
| A | HEC805 |
| A | HOH1357 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEC A 805 |
| Chain | Residue |
| A | THR278 |
| A | MET279 |
| A | HIS286 |
| A | ILE289 |
| A | PHE291 |
| A | HIS297 |
| A | GLN300 |
| A | ASP302 |
| A | ASN305 |
| A | CYS306 |
| A | CYS309 |
| A | HIS310 |
| A | HEC804 |
| A | HOH1097 |
| A | HOH1573 |
| site_id | AC6 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEC A 806 |
| Chain | Residue |
| A | LYS563 |
| A | HIS564 |
| A | ALA568 |
| A | LEU571 |
| A | ILE572 |
| A | SER578 |
| A | HEC807 |
| A | HOH1174 |
| A | HOH1364 |
| A | HOH1421 |
| A | HOH1473 |
| A | CYS189 |
| A | ASN251 |
| A | ALA495 |
| A | CYS496 |
| A | CYS499 |
| A | HIS500 |
| A | PHE504 |
| A | LEU535 |
| A | LEU560 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEC A 807 |
| Chain | Residue |
| A | TYR389 |
| A | PHE438 |
| A | HIS507 |
| A | HIS512 |
| A | CYS538 |
| A | THR540 |
| A | CYS541 |
| A | HIS542 |
| A | THR547 |
| A | TYR548 |
| A | ASN552 |
| A | LYS559 |
| A | LYS563 |
| A | HEC806 |
| A | HOH914 |
| A | HOH1343 |
| A | HOH1488 |
| A | HOH1561 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEC A 808 |
| Chain | Residue |
| A | ARG486 |
| A | HIS487 |
| A | SER490 |
| A | LEU535 |
| A | GLU557 |
| A | LEU560 |
| A | HIS561 |
| A | HIS564 |
| A | CYS576 |
| A | CYS579 |
| A | HIS580 |
| A | PHE583 |
| A | ASN584 |
| A | HIS666 |
| A | HEC809 |
| A | HOH902 |
| A | HOH909 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEC A 809 |
| Chain | Residue |
| A | HIS561 |
| A | LYS589 |
| A | THR613 |
| A | CYS614 |
| A | CYS617 |
| A | HIS618 |
| A | HIS659 |
| A | HIS666 |
| A | THR667 |
| A | HEC808 |
| A | HEC810 |
| A | EDO821 |
| A | HOH1204 |
| A | HOH1820 |
| site_id | BC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEC A 810 |
| Chain | Residue |
| A | THR611 |
| A | HIS618 |
| A | TYR624 |
| A | MET625 |
| A | VAL626 |
| A | HIS627 |
| A | PHE635 |
| A | CYS655 |
| A | CYS658 |
| A | HIS659 |
| A | HEC809 |
| A | HOH936 |
| A | HOH988 |
| A | HOH1103 |
| A | HOH1820 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 811 |
| Chain | Residue |
| A | ASP52 |
| A | ILE53 |
| A | GLU165 |
| A | HOH939 |
| A | HOH970 |
| A | HOH1451 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 812 |
| Chain | Residue |
| A | ASN231 |
| A | ASN234 |
| A | LYS237 |
| A | HOH1032 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 813 |
| Chain | Residue |
| A | ASP472 |
| A | GLN520 |
| A | HOH965 |
| A | HOH995 |
| A | HOH1063 |
| A | HOH1087 |
| A | HOH1490 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 814 |
| Chain | Residue |
| A | GLN651 |
| A | HOH1282 |
| A | HOH1323 |
| A | HOH1836 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 815 |
| Chain | Residue |
| A | GLU162 |
| A | GLU202 |
| A | HOH1040 |
| A | HOH1410 |
| A | HOH1452 |
| A | HOH1453 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 816 |
| Chain | Residue |
| A | GLY570 |
| A | THR654 |
| A | HOH1229 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 817 |
| Chain | Residue |
| A | ASP52 |
| A | THR54 |
| A | PHE68 |
| A | ASN136 |
| A | HOH996 |
| A | HOH1404 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 818 |
| Chain | Residue |
| A | GLY574 |
| A | CYS576 |
| A | VAL663 |
| A | ALA664 |
| A | ASP665 |
| A | HIS666 |
| A | HOH1505 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 819 |
| Chain | Residue |
| A | GLU586 |
| A | GLN623 |
| A | PHE656 |
| A | HOH1107 |
| A | HOH1126 |
| A | HOH1319 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 820 |
| Chain | Residue |
| A | SER304 |
| A | ASN305 |
| A | ALA457 |
| A | HOH1647 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 821 |
| Chain | Residue |
| A | HIS564 |
| A | VAL565 |
| A | TYR569 |
| A | ILE572 |
| A | GLY573 |
| A | HEC809 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 822 |
| Chain | Residue |
| A | THR326 |
| A | VAL463 |
| A | GLU505 |
| A | LYS508 |
| A | HOH1098 |
| A | HOH1366 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 823 |
| Chain | Residue |
| A | ASN331 |
| A | LYS470 |
| A | GLU503 |
| A | HOH1362 |
| site_id | CC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 824 |
| Chain | Residue |
| A | MET493 |
| A | THR494 |
| A | ALA497 |
| A | ALA502 |
| A | VAL533 |
| A | HOH1269 |
| A | HOH1303 |
