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4LIX

Crystal structure of ent-copalyl diphosphate synthase from Arabidopsis thaliana in complex with (S)-15-aza-14,15-dihydrogeranylgeranyl thiolodiphosphate at 1.55 A resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0003824molecular_functioncatalytic activity
A0008299biological_processisoprenoid biosynthetic process
A0009507cellular_componentchloroplast
A0009686biological_processgibberellin biosynthetic process
A0009740biological_processgibberellic acid mediated signaling pathway
A0009905molecular_functionent-copalyl diphosphate synthase activity
A0010333molecular_functionterpene synthase activity
A0016102biological_processditerpenoid biosynthetic process
A0016114biological_processterpenoid biosynthetic process
A0016829molecular_functionlyase activity
A0016853molecular_functionisomerase activity
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues14
DetailsBINDING SITE FOR RESIDUE AG8 A 901
ChainResidue
AILE208
ALYS463
ATRP464
AHOH1498
AHOH1531
AHOH1544
AGLY209
ALYS245
ATHR260
AHIS263
APHE329
ATRP333
APHE412
AASN417

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE PO4 A 902
ChainResidue
AHIS182
ALYS186
ASER579
AHIS580
ASER663
AHIS664
AHOH1279
AHOH1562
AHOH1666

site_idAC3
Number of Residues9
DetailsBINDING SITE FOR RESIDUE GOL A 903
ChainResidue
AARG192
APRO229
AHIS789
AGLN791
ATHR792
AHOH1030
AHOH1082
AHOH1200
AHOH1419

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:21602811, ECO:0007744|PDB:3PYA
ChainResidueDetails
ALYS245
ALYS463

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:C7BKP9
ChainResidueDetails
AASP377
AASP379

227111

PDB entries from 2024-11-06

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