4LIS
Crystal Structure of UDP-galactose-4-epimerase from Aspergillus nidulans
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003978 | molecular_function | UDP-glucose 4-epimerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005996 | biological_process | monosaccharide metabolic process |
| A | 0006012 | biological_process | galactose metabolic process |
| A | 0016853 | molecular_function | isomerase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003978 | molecular_function | UDP-glucose 4-epimerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005996 | biological_process | monosaccharide metabolic process |
| B | 0006012 | biological_process | galactose metabolic process |
| B | 0016853 | molecular_function | isomerase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003978 | molecular_function | UDP-glucose 4-epimerase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0005996 | biological_process | monosaccharide metabolic process |
| C | 0006012 | biological_process | galactose metabolic process |
| C | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE UPG A 401 |
| Chain | Residue |
| A | LYS88 |
| A | LEU235 |
| A | LEU236 |
| A | VAL237 |
| A | PHE238 |
| A | ALA249 |
| A | ARG251 |
| A | TYR253 |
| A | ARG313 |
| A | ASP316 |
| A | NAD402 |
| A | SER128 |
| A | ALA129 |
| A | TYR156 |
| A | PHE198 |
| A | ASN199 |
| A | ASN219 |
| A | LEU220 |
| A | LEU223 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE NAD A 402 |
| Chain | Residue |
| A | THR12 |
| A | GLY13 |
| A | TYR14 |
| A | ILE15 |
| A | ASP34 |
| A | ASN35 |
| A | TYR37 |
| A | ASN38 |
| A | SER39 |
| A | LEU60 |
| A | ASP61 |
| A | VAL62 |
| A | PHE84 |
| A | ALA85 |
| A | ALA86 |
| A | LYS88 |
| A | SER128 |
| A | TYR156 |
| A | LYS160 |
| A | TYR197 |
| A | PHE198 |
| A | PRO200 |
| A | UPG401 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 403 |
| Chain | Residue |
| A | GLU146 |
| A | HIS147 |
| A | ALA279 |
| A | ARG326 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 405 |
| Chain | Residue |
| A | ARG312 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 406 |
| Chain | Residue |
| A | PRO97 |
| A | GLN174 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE UDP B 401 |
| Chain | Residue |
| B | ASN199 |
| B | ASN219 |
| B | LEU220 |
| B | LEU223 |
| B | LEU236 |
| B | VAL237 |
| B | PHE238 |
| B | ALA249 |
| B | ARG251 |
| B | VAL290 |
| B | ARG313 |
| B | ASP316 |
| site_id | AC7 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE NAD B 402 |
| Chain | Residue |
| B | THR12 |
| B | GLY13 |
| B | TYR14 |
| B | ILE15 |
| B | ASP34 |
| B | ASN35 |
| B | TYR37 |
| B | ASN38 |
| B | SER39 |
| B | LEU60 |
| B | ASP61 |
| B | VAL62 |
| B | PHE84 |
| B | ALA85 |
| B | ALA86 |
| B | LYS88 |
| B | SER126 |
| B | SER127 |
| B | SER128 |
| B | TYR156 |
| B | LYS160 |
| B | TYR197 |
| B | PHE198 |
| B | PRO200 |
| B | HOH518 |
| B | HOH522 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD B 404 |
| Chain | Residue |
| B | ALA243 |
| B | ARG312 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD B 405 |
| Chain | Residue |
| B | GLN174 |
| C | LEU98 |
| site_id | BC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE UDP C 401 |
| Chain | Residue |
| C | PHE238 |
| C | ARG251 |
| C | VAL290 |
| C | ARG313 |
| C | ASP316 |
| C | HOH502 |
| C | ASN199 |
| C | TYR218 |
| C | ASN219 |
| C | LEU220 |
| C | LEU223 |
| C | LEU235 |
| C | LEU236 |
| C | VAL237 |
| site_id | BC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAD C 402 |
| Chain | Residue |
| C | THR12 |
| C | GLY13 |
| C | TYR14 |
| C | ILE15 |
| C | ASP34 |
| C | ASN35 |
| C | TYR37 |
| C | ASN38 |
| C | SER39 |
| C | LEU60 |
| C | ASP61 |
| C | VAL62 |
| C | PHE84 |
| C | ALA85 |
| C | ALA86 |
| C | LYS88 |
| C | SER126 |
| C | SER127 |
| C | SER128 |
| C | TYR156 |
| C | LYS160 |
| C | TYR197 |
| C | PRO200 |
| C | HOH511 |
| C | HOH515 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD C 404 |
| Chain | Residue |
| C | ALA243 |
| C | ARG312 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD C 405 |
| Chain | Residue |
| B | PRO97 |
| C | GLN174 |
