Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 1TZ A 401 |
| Chain | Residue |
| A | ASP33 |
| A | DMS406 |
| A | HOH811 |
| A | ASP35 |
| A | TYR79 |
| A | GLY80 |
| A | ASP81 |
| A | ASP219 |
| A | GLY221 |
| A | THR222 |
| A | TYR226 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 402 |
| Chain | Residue |
| A | VAL272 |
| A | TYR277 |
| A | ALA312 |
| A | SER329 |
| A | LYS330 |
| A | HOH524 |
| A | HOH684 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 403 |
| Chain | Residue |
| A | ALA187 |
| A | GLU196 |
| A | TRP197 |
| A | THR198 |
| A | ASP215 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 404 |
| Chain | Residue |
| A | SER297 |
| A | GLY301 |
| A | ILE302 |
| A | HOH536 |
| A | HOH563 |
| A | HOH567 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 405 |
| Chain | Residue |
| A | GLN140 |
| A | LYS142 |
| A | THR258 |
| A | HOH538 |
| A | HOH723 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DMS A 406 |
| Chain | Residue |
| A | ASP81 |
| A | GLY221 |
| A | THR222 |
| A | THR223 |
| A | 1TZ401 |
| A | HOH733 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE DMS A 407 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMS A 408 |
| Chain | Residue |
| A | ALA237 |
| A | SER240 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 409 |
| Chain | Residue |
| A | ALA257 |
| A | THR258 |
| A | LEU259 |
| A | ASP276 |
| A | ASP279 |
| A | HOH741 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 410 |
| Chain | Residue |
| A | CYS255 |
| A | ASP279 |
| A | GLY281 |
| A | CYS290 |
| A | HOH830 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 311 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {} |
