4LGV

X-ray crystal structure of Glucose-6-phosphate 1-dehydrogenase from Mycobacterium avium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
A	0005829	cellular_component	cytosol
A	0006006	biological_process	glucose metabolic process
A	0006098	biological_process	pentose-phosphate shunt
A	0009051	biological_process	pentose-phosphate shunt, oxidative branch
A	0016491	molecular_function	oxidoreductase activity
A	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
A	0050661	molecular_function	NADP binding
B	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
B	0005829	cellular_component	cytosol
B	0006006	biological_process	glucose metabolic process
B	0006098	biological_process	pentose-phosphate shunt
B	0009051	biological_process	pentose-phosphate shunt, oxidative branch
B	0016491	molecular_function	oxidoreductase activity
B	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
B	0050661	molecular_function	NADP binding
C	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
C	0005829	cellular_component	cytosol
C	0006006	biological_process	glucose metabolic process
C	0006098	biological_process	pentose-phosphate shunt
C	0009051	biological_process	pentose-phosphate shunt, oxidative branch
C	0016491	molecular_function	oxidoreductase activity
C	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
C	0050661	molecular_function	NADP binding
D	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
D	0005829	cellular_component	cytosol
D	0006006	biological_process	glucose metabolic process
D	0006098	biological_process	pentose-phosphate shunt
D	0009051	biological_process	pentose-phosphate shunt, oxidative branch
D	0016491	molecular_function	oxidoreductase activity
D	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
D	0050661	molecular_function	NADP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 501

Chain	Residue
A	ARG61
A	ASP73
A	ASP77
B	ASP50
C	PRO286

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 502

Chain	Residue
A	ARG32
A	GLU390
A	ARG393

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 503

Chain	Residue
A	ASP20
A	GLY19

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 502

Chain	Residue
B	ARG432
B	HIS434
D	ASN344
D	HOH650
D	HOH680

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO C 501

Chain	Residue
C	LEU39
C	GLU40
C	HIS41
C	PHE403

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site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL C 502

Chain	Residue
C	HIS335

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site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C 503

Chain	Residue
C	ARG317
C	GLN457

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site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 501

Chain	Residue
D	HIS335

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Functional Information from PROSITE/UniProt

site_id	PS00069
Number of Residues	7
Details	G6P_DEHYDROGENASE Glucose-6-phosphate dehydrogenase active site. DHFLGKQ

Chain	Residue	Details
A	ASP171-GLN177

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