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4LG1

Human Methyltransferase-Like Protein 21D

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006338biological_processchromatin remodeling
A0008168molecular_functionmethyltransferase activity
A0008276molecular_functionprotein methyltransferase activity
A0016279molecular_functionprotein-lysine N-methyltransferase activity
A0018022biological_processpeptidyl-lysine methylation
A0018023biological_processpeptidyl-lysine trimethylation
A0032259biological_processmethylation
A0032780biological_processnegative regulation of ATP-dependent activity
A0032991cellular_componentprotein-containing complex
A0042054molecular_functionhistone methyltransferase activity
A0051117molecular_functionATPase binding
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006338biological_processchromatin remodeling
B0008168molecular_functionmethyltransferase activity
B0008276molecular_functionprotein methyltransferase activity
B0016279molecular_functionprotein-lysine N-methyltransferase activity
B0018022biological_processpeptidyl-lysine methylation
B0018023biological_processpeptidyl-lysine trimethylation
B0032259biological_processmethylation
B0032780biological_processnegative regulation of ATP-dependent activity
B0032991cellular_componentprotein-containing complex
B0042054molecular_functionhistone methyltransferase activity
B0051117molecular_functionATPase binding
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006338biological_processchromatin remodeling
C0008168molecular_functionmethyltransferase activity
C0008276molecular_functionprotein methyltransferase activity
C0016279molecular_functionprotein-lysine N-methyltransferase activity
C0018022biological_processpeptidyl-lysine methylation
C0018023biological_processpeptidyl-lysine trimethylation
C0032259biological_processmethylation
C0032780biological_processnegative regulation of ATP-dependent activity
C0032991cellular_componentprotein-containing complex
C0042054molecular_functionhistone methyltransferase activity
C0051117molecular_functionATPase binding
Functional Information from PDB Data
site_idAC1
Number of Residues18
DetailsBINDING SITE FOR RESIDUE SAM A 301
ChainResidue
AVAL41
ALYS125
ATRP126
AALA143
AASP144
ATYR147
ATYR148
AHOH416
AHOH417
AHOH452
ATRP43
AALA46
AGLY75
ASER76
AGLY77
AASP96
ALEU97
ALEU124

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 302
ChainResidue
ALYS200
ALEU203
AGLU213
AILE215
AHIS216
AHOH404

site_idAC3
Number of Residues18
DetailsBINDING SITE FOR RESIDUE SAM B 301
ChainResidue
BVAL41
BTRP43
BALA46
BGLY75
BSER76
BGLY77
BASP96
BLEU97
BLEU124
BLYS125
BTRP126
BALA143
BASP144
BTYR147
BTYR148
BHOH403
BHOH422
BHOH468

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO B 302
ChainResidue
BSER59
BHIS64
BHOH419
BHOH445
BHOH457

site_idAC5
Number of Residues18
DetailsBINDING SITE FOR RESIDUE SAM C 301
ChainResidue
CVAL41
CTRP43
CALA46
CGLY75
CSER76
CGLY77
CASP96
CLEU97
CLEU124
CLYS125
CTRP126
CALA143
CASP144
CTYR147
CTYR148
CHOH407
CHOH409
CHOH429

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues18
DetailsBINDING: BINDING => ECO:0000269|Ref.9
ChainResidueDetails
ATRP43
BTRP126
BALA143
BTYR148
CTRP43
CGLY75
CASP96
CTRP126
CALA143
CTYR148
AGLY75
AASP96
ATRP126
AALA143
ATYR148
BTRP43
BGLY75
BASP96

site_idSWS_FT_FI2
Number of Residues3
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER8
BSER8
CSER8

226707

PDB entries from 2024-10-30

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