4LCM

Simvastatin Synthase (LOVD), from Aspergillus Terreus, LovD9 mutant (simh9014)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016787	molecular_function	hydrolase activity
A	0017000	biological_process	antibiotic biosynthetic process
A	0030639	biological_process	polyketide biosynthetic process
A	0050832	biological_process	defense response to fungus
A	0140735	biological_process	lovastatin biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0016787	molecular_function	hydrolase activity
B	0017000	biological_process	antibiotic biosynthetic process
B	0030639	biological_process	polyketide biosynthetic process
B	0050832	biological_process	defense response to fungus
B	0140735	biological_process	lovastatin biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0016787	molecular_function	hydrolase activity
C	0017000	biological_process	antibiotic biosynthetic process
C	0030639	biological_process	polyketide biosynthetic process
C	0050832	biological_process	defense response to fungus
C	0140735	biological_process	lovastatin biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
D	0016787	molecular_function	hydrolase activity
D	0017000	biological_process	antibiotic biosynthetic process
D	0030639	biological_process	polyketide biosynthetic process
D	0050832	biological_process	defense response to fungus
D	0140735	biological_process	lovastatin biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"PubMed","id":"17113998","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19875080","evidenceCode":"ECO:0000269"}]}

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Residue

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Chain

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