4LCL
Simvastatin Synthase (LOVD), from Aspergillus Terreus, LovD6 mutant (simh6208)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017000 | biological_process | antibiotic biosynthetic process |
| A | 0030639 | biological_process | polyketide biosynthetic process |
| A | 0050832 | biological_process | defense response to fungus |
| A | 0140735 | biological_process | lovastatin biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0017000 | biological_process | antibiotic biosynthetic process |
| B | 0030639 | biological_process | polyketide biosynthetic process |
| B | 0050832 | biological_process | defense response to fungus |
| B | 0140735 | biological_process | lovastatin biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IPA A 501 |
| Chain | Residue |
| A | SER76 |
| A | TYR188 |
| A | GLY364 |
| A | TRP390 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA B 501 |
| Chain | Residue |
| B | SER76 |
| B | TYR188 |
| B | TRP390 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"PubMed","id":"17113998","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19875080","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Binding site: {} |
| Chain | Residue | Details |
