Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS A 401 |
| Chain | Residue |
| A | ASP81 |
| A | GLY221 |
| A | THR222 |
| A | THR223 |
| A | 1TZ402 |
| A | 1TZ403 |
| A | HOH504 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 1TZ A 402 |
| Chain | Residue |
| A | ASP119 |
| A | THR223 |
| A | DMS401 |
| A | 1TZ403 |
| A | 1TZ404 |
| A | ASP15 |
| A | ALA16 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE 1TZ A 403 |
| Chain | Residue |
| A | ASP33 |
| A | ASP35 |
| A | TYR79 |
| A | GLY80 |
| A | ASP81 |
| A | PHE116 |
| A | ASP219 |
| A | GLY221 |
| A | THR222 |
| A | TYR226 |
| A | DMS401 |
| A | 1TZ402 |
| A | 1TZ404 |
| A | HOH781 |
| A | HOH810 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 1TZ A 404 |
| Chain | Residue |
| A | ASP15 |
| A | VAL248 |
| A | GLY249 |
| A | PHE280 |
| A | PRO282 |
| A | ILE283 |
| A | PHE291 |
| A | 1TZ402 |
| A | 1TZ403 |
| A | HOH767 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 405 |
| Chain | Residue |
| A | VAL272 |
| A | PRO274 |
| A | TYR277 |
| A | ALA312 |
| A | SER329 |
| A | LYS330 |
| A | HOH518 |
| A | HOH742 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 406 |
| Chain | Residue |
| A | SER297 |
| A | GLY301 |
| A | ILE302 |
| A | HOH520 |
| A | HOH570 |
| A | HOH683 |
| A | HOH684 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 311 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {} |
