4LBB

Crystal structure of human alpha-defensin 1 (HNP1) I20A mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0006952	biological_process	defense response
B	0005576	cellular_component	extracellular region
B	0006952	biological_process	defense response

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 101

Chain	Residue
A	PRO7
A	HOH208

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 101

Chain	Residue
A	ARG14
A	ARG15
B	ALA11
B	HOH210

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 102

Chain	Residue
B	ARG15

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 103

Chain	Residue
B	CYS2
B	HOH211

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site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 104

Chain	Residue
A	HOH209

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site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 105

Chain	Residue
A	GLY12
A	GLU13
B	GLY12
B	GLU13

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Functional Information from PROSITE/UniProt

site_id	PS00269
Number of Residues	29
Details	DEFENSIN Mammalian defensins signature. CyCripa.CiagerryGtCayqgrlwafCC

Chain	Residue	Details
A	CYS2-CYS30

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	58
Details	Peptide: {"description":"Neutrophil defensin 1","featureId":"PRO_0000006773"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	56
Details	Peptide: {"description":"Neutrophil defensin 2","featureId":"PRO_0000006774"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"ADP-ribosylarginine; by ART1","evidences":[{"source":"PubMed","id":"21904558","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"21904558","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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