Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008134 | molecular_function | transcription factor binding |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0031463 | cellular_component | Cul3-RING ubiquitin ligase complex |
| B | 0008134 | molecular_function | transcription factor binding |
| B | 0016567 | biological_process | protein ubiquitination |
| B | 0031463 | cellular_component | Cul3-RING ubiquitin ligase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 701 |
| Chain | Residue |
| A | ASN401 |
| A | LEU471 |
| A | TYR491 |
| A | PRO492 |
| A | GLU493 |
| A | ARG494 |
| A | HOH832 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 702 |
| Chain | Residue |
| A | THR609 |
| A | TYR329 |
| A | GLY372 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 703 |
| Chain | Residue |
| A | MET399 |
| A | TYR491 |
| A | ARG494 |
| A | GLU496 |
| A | ARG498 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 704 |
| Chain | Residue |
| A | ARG415 |
| A | PHE478 |
| A | ARG483 |
| A | SER508 |
| B | ASP385 |
| B | GLY386 |
| B | HOH887 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 1VV B 701 |
| Chain | Residue |
| B | TYR334 |
| B | ASN414 |
| B | ARG415 |
| B | GLY509 |
| B | ALA556 |
| B | TYR572 |
| B | SER602 |
| B | HOH871 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA B 702 |
| Chain | Residue |
| A | HOH889 |
| B | HOH884 |
| B | HOH885 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 703 |
| Chain | Residue |
| B | ASN401 |
| B | TYR491 |
| B | PRO492 |
| B | GLU493 |
| B | ARG494 |
| B | HOH830 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 90 |
| Details | Repeat: {"description":"Kelch 1"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 100 |
| Details | Repeat: {"description":"Kelch 2"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 92 |
| Details | Repeat: {"description":"Kelch 3"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 92 |
| Details | Repeat: {"description":"Kelch 4"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 92 |
| Details | Repeat: {"description":"Kelch 5"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 92 |
| Details | Repeat: {"description":"Kelch 6"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Site: {"description":"Sensor for electrophilic agents","evidences":[{"source":"UniProtKB","id":"Q9Z2X8","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"S-cGMP-cysteine","evidences":[{"source":"UniProtKB","id":"Q9Z2X8","evidenceCode":"ECO:0000250"}]} |
