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4L5Y

Methylthioadenosine phosphorylase from Schistosoma mansoni in APO form

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006166biological_processpurine ribonucleoside salvage
A0009116biological_processnucleoside metabolic process
A0016757molecular_functionglycosyltransferase activity
A0016763molecular_functionpentosyltransferase activity
A0017061molecular_functionS-methyl-5-thioadenosine phosphorylase activity
A0019509biological_processL-methionine salvage from methylthioadenosine
B0003824molecular_functioncatalytic activity
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006166biological_processpurine ribonucleoside salvage
B0009116biological_processnucleoside metabolic process
B0016757molecular_functionglycosyltransferase activity
B0016763molecular_functionpentosyltransferase activity
B0017061molecular_functionS-methyl-5-thioadenosine phosphorylase activity
B0019509biological_processL-methionine salvage from methylthioadenosine
C0003824molecular_functioncatalytic activity
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006166biological_processpurine ribonucleoside salvage
C0009116biological_processnucleoside metabolic process
C0016757molecular_functionglycosyltransferase activity
C0016763molecular_functionpentosyltransferase activity
C0017061molecular_functionS-methyl-5-thioadenosine phosphorylase activity
C0019509biological_processL-methionine salvage from methylthioadenosine
D0003824molecular_functioncatalytic activity
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0006166biological_processpurine ribonucleoside salvage
D0009116biological_processnucleoside metabolic process
D0016757molecular_functionglycosyltransferase activity
D0016763molecular_functionpentosyltransferase activity
D0017061molecular_functionS-methyl-5-thioadenosine phosphorylase activity
D0019509biological_processL-methionine salvage from methylthioadenosine
E0003824molecular_functioncatalytic activity
E0005634cellular_componentnucleus
E0005737cellular_componentcytoplasm
E0005829cellular_componentcytosol
E0006166biological_processpurine ribonucleoside salvage
E0009116biological_processnucleoside metabolic process
E0016757molecular_functionglycosyltransferase activity
E0016763molecular_functionpentosyltransferase activity
E0017061molecular_functionS-methyl-5-thioadenosine phosphorylase activity
E0019509biological_processL-methionine salvage from methylthioadenosine
F0003824molecular_functioncatalytic activity
F0005634cellular_componentnucleus
F0005737cellular_componentcytoplasm
F0005829cellular_componentcytosol
F0006166biological_processpurine ribonucleoside salvage
F0009116biological_processnucleoside metabolic process
F0016757molecular_functionglycosyltransferase activity
F0016763molecular_functionpentosyltransferase activity
F0017061molecular_functionS-methyl-5-thioadenosine phosphorylase activity
F0019509biological_processL-methionine salvage from methylthioadenosine
Functional Information from PDB Data
site_idAC1
Number of Residues10
DetailsBINDING SITE FOR RESIDUE PO4 A 301
ChainResidue
AGLY11
AHOH529
ASER12
AARG54
AHIS55
AASN87
AALA88
ATHR207
AHOH417
AHOH486

site_idAC2
Number of Residues10
DetailsBINDING SITE FOR RESIDUE PO4 B 301
ChainResidue
BGLY11
BSER12
BARG54
BHIS55
BASN87
BALA88
BTHR207
BHOH450
BHOH485
BHOH492

site_idAC3
Number of Residues10
DetailsBINDING SITE FOR RESIDUE PO4 C 301
ChainResidue
CGLY11
CSER12
CARG54
CHIS55
CASN87
CALA88
CTHR207
CHOH409
CHOH417
CHOH420

site_idAC4
Number of Residues9
DetailsBINDING SITE FOR RESIDUE PO4 D 301
ChainResidue
DGLY11
DSER12
DARG54
DHIS55
DASN87
DALA88
DTHR207
DHOH403
DHOH467

site_idAC5
Number of Residues9
DetailsBINDING SITE FOR RESIDUE PO4 E 301
ChainResidue
EGLY11
ESER12
EARG54
EHIS55
EASN87
EALA88
ETHR207
EHOH406
EHOH484

site_idAC6
Number of Residues11
DetailsBINDING SITE FOR RESIDUE PO4 F 301
ChainResidue
FGLY11
FSER12
FARG54
FHIS55
FASN87
FALA88
FTHR207
FHOH428
FHOH435
FHOH437
FHOH443

Functional Information from PROSITE/UniProt
site_idPS01240
Number of Residues41
DetailsPNP_MTAP_2 Purine and other phosphorylases family 2 signature. LprhGkgHlIppseVnyrAn.VwAlkdlGcth.ILatNAcGSL
ChainResidueDetails
ALEU52-LEU92

227111

PDB entries from 2024-11-06

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