4L39
Crystal structure of GH3.12 from Arabidopsis thaliana in complex with AMPCPP and salicylate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006952 | biological_process | defense response |
| A | 0009626 | biological_process | plant-type hypersensitive response |
| A | 0009863 | biological_process | salicylic acid mediated signaling pathway |
| A | 0010112 | biological_process | regulation of systemic acquired resistance |
| A | 0016046 | biological_process | detection of fungus |
| A | 0016874 | molecular_function | ligase activity |
| A | 0016881 | molecular_function | acid-amino acid ligase activity |
| A | 0018874 | biological_process | benzoate metabolic process |
| A | 0034052 | biological_process | positive regulation of plant-type hypersensitive response |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0052625 | molecular_function | N-(4-aminobenzoyl)-L-glutamate synthetase activity |
| A | 0052626 | molecular_function | N-benzoyl-L-glutamate synthetase activity |
| A | 0052627 | molecular_function | N-vanillate-L-glutamate synthetase activity |
| A | 0052628 | molecular_function | N-(4-hydroxybenzoyl)-L-glutamate synthetase activity |
| A | 0071456 | biological_process | cellular response to hypoxia |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006952 | biological_process | defense response |
| B | 0009626 | biological_process | plant-type hypersensitive response |
| B | 0009863 | biological_process | salicylic acid mediated signaling pathway |
| B | 0010112 | biological_process | regulation of systemic acquired resistance |
| B | 0016046 | biological_process | detection of fungus |
| B | 0016874 | molecular_function | ligase activity |
| B | 0016881 | molecular_function | acid-amino acid ligase activity |
| B | 0018874 | biological_process | benzoate metabolic process |
| B | 0034052 | biological_process | positive regulation of plant-type hypersensitive response |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 0052625 | molecular_function | N-(4-aminobenzoyl)-L-glutamate synthetase activity |
| B | 0052626 | molecular_function | N-benzoyl-L-glutamate synthetase activity |
| B | 0052627 | molecular_function | N-vanillate-L-glutamate synthetase activity |
| B | 0052628 | molecular_function | N-(4-hydroxybenzoyl)-L-glutamate synthetase activity |
| B | 0071456 | biological_process | cellular response to hypoxia |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 601 |
| Chain | Residue |
| A | GLU329 |
| A | VAL396 |
| A | APC603 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SAL A 602 |
| Chain | Residue |
| A | LEU116 |
| A | TYR120 |
| A | ARG123 |
| A | THR324 |
| A | GLY326 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE APC A 603 |
| Chain | Residue |
| A | VAL299 |
| A | THR301 |
| A | THR324 |
| A | GLY326 |
| A | SER327 |
| A | SER328 |
| A | TYR347 |
| A | ASP398 |
| A | PHE414 |
| A | MG601 |
| A | HOH755 |
| A | HOH766 |
| A | SER95 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SAL B 601 |
| Chain | Residue |
| B | TYR120 |
| B | ARG123 |
| B | ILE217 |
| B | THR324 |
| B | APC602 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE APC B 602 |
| Chain | Residue |
| B | SER95 |
| B | SER96 |
| B | LYS104 |
| B | THR301 |
| B | THR324 |
| B | TYR325 |
| B | GLY326 |
| B | SER327 |
| B | SER328 |
| B | TYR347 |
| B | ASP398 |
| B | LYS428 |
| B | SAL601 |
| B | HOH755 |
| B | HOH765 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22628555","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4EQ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4EQL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22628555","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4EPM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4EQ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4EQL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22628555","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4EQ4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
