4L21

Crystal structure of Cimex nitrophorin F64V mutant ferrous NO complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004439	molecular_function	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
A	0005506	molecular_function	iron ion binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0016791	molecular_function	phosphatase activity
A	0020037	molecular_function	heme binding
A	0030185	biological_process	nitric oxide transport
A	0042311	biological_process	vasodilation
A	0044552	biological_process	vasodilation in another organism
A	0046856	biological_process	phosphatidylinositol dephosphorylation
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEM A 301

Chain	Residue
A	SER16
A	VAL64
A	GLN65
A	LYS75
A	ASN78
A	THR87
A	TYR89
A	NO302
A	HOH520
A	HOH546
A	GLU19
A	LEU28
A	VAL44
A	PHE49
A	ASP52
A	GLY57
A	SNC60
A	VAL61

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NO A 302

Chain	Residue
A	VAL44
A	ILE80
A	HEM301

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: proximal binding residue => ECO:0000269|PubMed:15637157, ECO:0007744|PDB:1NTF, ECO:0007744|PDB:2IMQ

Chain	Residue	Details
A	SNC60

---