4L1U

Crystal Structure of Human Rtf1 Plus3 Domain in Complex with Spt5 CTR Phosphopeptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
B	0003677	molecular_function	DNA binding
C	0003677	molecular_function	DNA binding
D	0003677	molecular_function	DNA binding
E	0003677	molecular_function	DNA binding
F	0003677	molecular_function	DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 501

Chain	Residue
A	ARG401
A	ASP433
A	ARG435
A	PHE437

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 502

Chain	Residue
A	ARG366
A	SER443
A	ASN444
A	GLN445
H	ARG783

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 503

Chain	Residue
A	VAL414
A	TYR415
A	GLN416

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 504

Chain	Residue
A	ARG363
A	SER365
A	HIS367
A	LYS368
C	GLN416

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B 501

Chain	Residue
B	ARG366
B	GLU370
B	GLY418
B	HOH602
D	ARG366
D	GLU370
D	GLY418
D	HOH603

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 502

Chain	Residue
B	THR411
B	ALA412
B	ARG438

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 503

Chain	Residue
B	HIS374
B	THR422
B	ASN423
B	LYS424

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 504

Chain	Residue
B	HIS394
B	ASN395

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 B 505

Chain	Residue
B	ARG401
B	LEU428
B	ARG429
B	HIS430
B	ASP433
B	ARG435
B	PHE437

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 506

Chain	Residue
B	THR448
B	GLU449
B	HOH608

---

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 B 507

Chain	Residue
B	GLN416

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 501

Chain	Residue
C	ARG363
C	SER365
C	LYS368

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 502

Chain	Residue
C	HIS374
C	THR422
C	ASN423
C	LYS424

---

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 503

Chain	Residue
C	THR448
C	GLU449

---

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 504

Chain	Residue
A	ARG366
A	GLU370
C	ARG366
C	GLU370
C	GLY418
C	HOH612

---

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 505

Chain	Residue
C	PHE377
C	PHE378
C	ALA379
C	LYS380
F	HIS394

---

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 501

Chain	Residue
B	GLN416
D	ARG363
D	SER365

---

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 D 502

Chain	Residue
D	ARG366
D	TYR400
D	SER443
D	ASN444
D	GLN445
G	ARG783

---

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 503

Chain	Residue
D	ARG401
D	LYS454
D	HOH618

---

site_id	CC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 504

Chain	Residue
D	ARG361
D	ASN473
F	ASN432

---

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 505

Chain	Residue
D	ARG401
D	HIS430
D	ASP433
D	ARG435
D	PHE437

---

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 506

Chain	Residue
D	THR448
D	GLU449

---

site_id	CC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 507

Chain	Residue
D	TYR415
D	GLN416
D	ARG421

---

site_id	CC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL D 508

Chain	Residue
B	ARG363
B	SER365
B	LYS368
B	ARG371
B	HOH615
D	GLN416

---

site_id	CC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 501

Chain	Residue
E	ARG401
E	LYS454

---

site_id	CC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 E 502

Chain	Residue
E	GLU370
E	GLY418
E	HOH611
I	ARG783
E	ARG366

---

site_id	CC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 503

Chain	Residue
B	ASN393
E	HIS394
E	ASN395

---

site_id	DC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 E 504

Chain	Residue
E	ARG401
E	ARG429
E	HIS430
E	ASP433
E	ARG435
E	PHE437

---

site_id	DC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 505

Chain	Residue
E	THR448
E	GLU449
E	HOH609

---

site_id	DC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 F 501

Chain	Residue
F	ARG366
F	GLU370
F	GLY418
J	SER782

---

site_id	DC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 F 502

Chain	Residue
F	THR448
F	GLU449

---

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 F 503

Chain	Residue
F	THR411
F	ALA412
F	LYS413
F	ARG438

---

site_id	DC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL F 504

Chain	Residue
F	SER365
F	LYS368
F	ARG371

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	131
Details	Domain: {"description":"Plus3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00693","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine; by CDK9","evidences":[{"source":"PubMed","id":"10757782","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16427012","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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