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4L1L

Rat PKC C2 domain bound to CD

Functional Information from GO Data
ChainGOidnamespacecontents
A0004674molecular_functionprotein serine/threonine kinase activity
A0005524molecular_functionATP binding
A0006468biological_processprotein phosphorylation
Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE SO4 A 301
ChainResidue
AARG239
APHE261
AGLY262
AGLU265
AASN287
AHOH426
AHOH435
AHOH534

site_idAC2
Number of Residues8
DetailsBINDING SITE FOR RESIDUE SO4 A 302
ChainResidue
ALYS197
ALYS199
AASN206
ALYS209
AGLN222
AHOH468
AHOH508
ALYS181

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 303
ChainResidue
ATYR195
ALYS197
ALYS209
ALYS211
AHOH459
AHOH499

site_idAC4
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 304
ChainResidue
ALYS172
ALYS230
AARG252
AASN253
AHOH451
AHOH527

site_idAC5
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 A 305
ChainResidue
AASP187
AARG249
ATHR250
ATHR251
AHOH410
AHOH443
AHOH445

site_idAC6
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CD A 306
ChainResidue
AASP187
AASP193
AASP246
ATRP247
AASP248
AHOH410

site_idAC7
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CD A 307
ChainResidue
AMET186
AASP187
AASP246
AASP248
AASP254
AHOH443

site_idAC8
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CD A 308
ChainResidue
AASP248
ATHR251
AARG252
AASP254

site_idAC9
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CD A 309
ChainResidue
AASP187
AASP193
ASER217
AHOH408
AHOH419
AHOH522

site_idBC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CD A 310
ChainResidue
ATHR156
AGLU157
AASN279
AGLU282
AHOH540
AHOH541

site_idBC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CD A 311
ChainResidue
AGLU265
AHOH420
AHOH501
AHOH511

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:10562545
ChainResidueDetails
AMET186

site_idSWS_FT_FI2
Number of Residues7
DetailsBINDING: BINDING => ECO:0000269|PubMed:10562545, ECO:0000269|PubMed:19346474
ChainResidueDetails
AASP187
AASP193
AASP246
ATRP247
AASP248
AARG252
AASP254

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:19346474
ChainResidueDetails
ATYR195
ATRP245

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:22673903
ChainResidueDetails
ASER226

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PDB entries from 2024-10-30

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