4KYP
Beta-Scorpion Toxin folded in the periplasm of E.coli
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0008200 | molecular_function | ion channel inhibitor activity |
| A | 0019871 | molecular_function | sodium channel inhibitor activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0008200 | molecular_function | ion channel inhibitor activity |
| B | 0019871 | molecular_function | sodium channel inhibitor activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0008200 | molecular_function | ion channel inhibitor activity |
| C | 0019871 | molecular_function | sodium channel inhibitor activity |
| D | 0005576 | cellular_component | extracellular region |
| D | 0008200 | molecular_function | ion channel inhibitor activity |
| D | 0019871 | molecular_function | sodium channel inhibitor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGE A 101 |
| Chain | Residue |
| A | TYR5 |
| A | TYR5 |
| A | TRP44 |
| A | TRP44 |
| A | LYS62 |
| A | HOH281 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PGE C 101 |
| Chain | Residue |
| C | TYR5 |
| C | TRP44 |
| C | LYS62 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PG4 D 101 |
| Chain | Residue |
| B | TYR5 |
| B | TRP44 |
| B | LYS62 |
| B | THR65 |
| B | HOH139 |
| D | TYR5 |
| D | TRP44 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 272 |
| Details | Domain: {"description":"LCN-type CS-alpha/beta","evidences":[{"source":"PROSITE-ProRule","id":"PRU01210","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Site: {"description":"May be involved in voltage sensor trapping upon activation of sodium channel"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"May interact with a positively charged residue of the receptor site"} |
| Chain | Residue | Details |
