4KYP

Beta-Scorpion Toxin folded in the periplasm of E.coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0008200	molecular_function	ion channel inhibitor activity
A	0017080	molecular_function	sodium channel regulator activity
A	0019871	molecular_function	sodium channel inhibitor activity
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity
A	0099106	molecular_function	ion channel regulator activity
B	0005576	cellular_component	extracellular region
B	0008200	molecular_function	ion channel inhibitor activity
B	0017080	molecular_function	sodium channel regulator activity
B	0019871	molecular_function	sodium channel inhibitor activity
B	0035821	biological_process	modulation of process of another organism
B	0090729	molecular_function	toxin activity
B	0099106	molecular_function	ion channel regulator activity
C	0005576	cellular_component	extracellular region
C	0008200	molecular_function	ion channel inhibitor activity
C	0017080	molecular_function	sodium channel regulator activity
C	0019871	molecular_function	sodium channel inhibitor activity
C	0035821	biological_process	modulation of process of another organism
C	0090729	molecular_function	toxin activity
C	0099106	molecular_function	ion channel regulator activity
D	0005576	cellular_component	extracellular region
D	0008200	molecular_function	ion channel inhibitor activity
D	0017080	molecular_function	sodium channel regulator activity
D	0019871	molecular_function	sodium channel inhibitor activity
D	0035821	biological_process	modulation of process of another organism
D	0090729	molecular_function	toxin activity
D	0099106	molecular_function	ion channel regulator activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PGE A 101

Chain	Residue
A	TYR5
A	TYR5
A	TRP44
A	TRP44
A	LYS62
A	HOH281

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PGE C 101

Chain	Residue
C	TYR5
C	TRP44
C	LYS62

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PG4 D 101

Chain	Residue
B	TYR5
B	TRP44
B	LYS62
B	THR65
B	HOH139
D	TYR5
D	TRP44

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	272
Details	Domain: {"description":"LCN-type CS-alpha/beta","evidences":[{"source":"PROSITE-ProRule","id":"PRU01210","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Site: {"description":"May be involved in voltage sensor trapping upon activation of sodium channel"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Site: {"description":"May interact with a positively charged residue of the receptor site"}

Chain

Residue

Details

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