4KWT
Crystal structure of unliganded anabolic ornithine carbamoyltransferase from Vibrio vulnificus at 1.86 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0006526 | biological_process | L-arginine biosynthetic process |
| A | 0006591 | biological_process | ornithine metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| A | 0019240 | biological_process | citrulline biosynthetic process |
| A | 0042450 | biological_process | L-arginine biosynthetic process via ornithine |
| B | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0006526 | biological_process | L-arginine biosynthetic process |
| B | 0006591 | biological_process | ornithine metabolic process |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016597 | molecular_function | amino acid binding |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| B | 0019240 | biological_process | citrulline biosynthetic process |
| B | 0042450 | biological_process | L-arginine biosynthetic process via ornithine |
| C | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0006526 | biological_process | L-arginine biosynthetic process |
| C | 0006591 | biological_process | ornithine metabolic process |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0016597 | molecular_function | amino acid binding |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| C | 0019240 | biological_process | citrulline biosynthetic process |
| C | 0042450 | biological_process | L-arginine biosynthetic process via ornithine |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 401 |
| Chain | Residue |
| A | SER57 |
| A | THR60 |
| A | ARG108 |
| A | HIS135 |
| A | ARG320 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 402 |
| Chain | Residue |
| A | LEU13 |
| A | PHE134 |
| A | PRO136 |
| A | SER173 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 401 |
| Chain | Residue |
| B | LEU13 |
| B | PHE134 |
| B | PRO136 |
| B | SER173 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL C 401 |
| Chain | Residue |
| C | SER57 |
| C | THR60 |
| C | ARG108 |
| C | HIS135 |
| C | ARG320 |
| C | HOH536 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 402 |
| Chain | Residue |
| C | LEU13 |
| C | PHE134 |
| C | PRO136 |
| C | SER173 |
| C | HOH516 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG C 403 |
| Chain | Residue |
| C | MET259 |
| C | GLY266 |
| C | ASN267 |
| C | PRO268 |
| C | HIS310 |
Functional Information from PROSITE/UniProt
| site_id | PS00097 |
| Number of Residues | 8 |
| Details | CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FeKaSTRT |
| Chain | Residue | Details |
| A | PHE53-THR60 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"SEP-2012","submissionDatabase":"PDB data bank","title":"Structural studies of ornithine carbamoyltransferase from various pathogens.","authors":["Shabalin I.G.","Winsor J.","Grimshaw S.","Osinski T.","Chordia M.D.","Anderson W.F.","Minor W."]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2013","submissionDatabase":"PDB data bank","title":"Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis.","authors":["Shabalin I.G.","Winsor J.","Grimshaw S.","Minor W."]}},{"source":"PDB","id":"4H31","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JFR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JQO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"SEP-2012","submissionDatabase":"PDB data bank","title":"Structural studies of ornithine carbamoyltransferase from various pathogens.","authors":["Shabalin I.G.","Winsor J.","Grimshaw S.","Osinski T.","Chordia M.D.","Anderson W.F.","Minor W."]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2013","submissionDatabase":"PDB data bank","title":"Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis.","authors":["Shabalin I.G.","Winsor J.","Grimshaw S.","Minor W."]}},{"source":"PDB","id":"4H31","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JQO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"SEP-2012","submissionDatabase":"PDB data bank","title":"Structural studies of ornithine carbamoyltransferase from various pathogens.","authors":["Shabalin I.G.","Winsor J.","Grimshaw S.","Osinski T.","Chordia M.D.","Anderson W.F.","Minor W."]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2013","submissionDatabase":"PDB data bank","title":"Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis.","authors":["Shabalin I.G.","Winsor J.","Grimshaw S.","Minor W."]}},{"source":"PDB","id":"4H31","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JQO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
