4KWT
Crystal structure of unliganded anabolic ornithine carbamoyltransferase from Vibrio vulnificus at 1.86 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0006526 | biological_process | arginine biosynthetic process |
| A | 0006591 | biological_process | ornithine metabolic process |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| A | 0019240 | biological_process | citrulline biosynthetic process |
| A | 0042450 | biological_process | arginine biosynthetic process via ornithine |
| B | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0006526 | biological_process | arginine biosynthetic process |
| B | 0006591 | biological_process | ornithine metabolic process |
| B | 0016597 | molecular_function | amino acid binding |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| B | 0019240 | biological_process | citrulline biosynthetic process |
| B | 0042450 | biological_process | arginine biosynthetic process via ornithine |
| C | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0006526 | biological_process | arginine biosynthetic process |
| C | 0006591 | biological_process | ornithine metabolic process |
| C | 0016597 | molecular_function | amino acid binding |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| C | 0019240 | biological_process | citrulline biosynthetic process |
| C | 0042450 | biological_process | arginine biosynthetic process via ornithine |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 401 |
| Chain | Residue |
| A | SER57 |
| A | THR60 |
| A | ARG108 |
| A | HIS135 |
| A | ARG320 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 402 |
| Chain | Residue |
| A | LEU13 |
| A | PHE134 |
| A | PRO136 |
| A | SER173 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 401 |
| Chain | Residue |
| B | LEU13 |
| B | PHE134 |
| B | PRO136 |
| B | SER173 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL C 401 |
| Chain | Residue |
| C | SER57 |
| C | THR60 |
| C | ARG108 |
| C | HIS135 |
| C | ARG320 |
| C | HOH536 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 402 |
| Chain | Residue |
| C | LEU13 |
| C | PHE134 |
| C | PRO136 |
| C | SER173 |
| C | HOH516 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG C 403 |
| Chain | Residue |
| C | MET259 |
| C | GLY266 |
| C | ASN267 |
| C | PRO268 |
| C | HIS310 |
Functional Information from PROSITE/UniProt
| site_id | PS00097 |
| Number of Residues | 8 |
| Details | CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FeKaSTRT |
| Chain | Residue | Details |
| A | PHE53-THR60 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|Ref.3, ECO:0000269|Ref.4, ECO:0007744|PDB:4H31, ECO:0007744|PDB:4JFR, ECO:0007744|PDB:4JHX, ECO:0007744|PDB:4JQO |
| Chain | Residue | Details |
| A | SER57 | |
| C | ARG108 | |
| C | HIS135 | |
| C | CYS275 | |
| A | ARG108 | |
| A | HIS135 | |
| A | CYS275 | |
| B | SER57 | |
| B | ARG108 | |
| B | HIS135 | |
| B | CYS275 | |
| C | SER57 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|Ref.3, ECO:0000269|Ref.4, ECO:0007744|PDB:4H31, ECO:0007744|PDB:4JQO |
| Chain | Residue | Details |
| A | GLN84 | |
| B | GLN84 | |
| C | GLN84 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|Ref.3, ECO:0000269|Ref.4, ECO:0007744|PDB:4H31, ECO:0007744|PDB:4JHX, ECO:0007744|PDB:4JQO |
| Chain | Residue | Details |
| A | ASN169 | |
| C | ASP233 | |
| C | SER237 | |
| C | ARG320 | |
| A | ASP233 | |
| A | SER237 | |
| A | ARG320 | |
| B | ASN169 | |
| B | ASP233 | |
| B | SER237 | |
| B | ARG320 | |
| C | ASN169 |
