Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE 1TZ A 401 |
| Chain | Residue |
| A | ASP33 |
| A | THR222 |
| A | TYR226 |
| A | 1TZ402 |
| A | DMS403 |
| A | HOH793 |
| A | HOH795 |
| A | ASP35 |
| A | TYR79 |
| A | GLY80 |
| A | ASP81 |
| A | SER83 |
| A | PHE116 |
| A | ASP219 |
| A | GLY221 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 1TZ A 402 |
| Chain | Residue |
| A | ASP15 |
| A | ALA16 |
| A | ASP119 |
| A | THR223 |
| A | 1TZ401 |
| A | DMS403 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS A 403 |
| Chain | Residue |
| A | ASP81 |
| A | GLY221 |
| A | THR222 |
| A | THR223 |
| A | 1TZ401 |
| A | 1TZ402 |
| A | HOH504 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS A 404 |
| Chain | Residue |
| A | ILE10 |
| A | GLU118 |
| A | ASP119 |
| A | SER120 |
| A | THR121 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMS A 405 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS A 406 |
| Chain | Residue |
| A | ALA257 |
| A | LEU259 |
| A | ASP276 |
| A | ASP279 |
| A | HOH583 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS A 407 |
| Chain | Residue |
| A | SER233 |
| A | ALA237 |
| A | ALA242 |
| A | HOH588 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 408 |
| Chain | Residue |
| A | ILE18 |
| A | ASN31 |
| A | HOH517 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 409 |
| Chain | Residue |
| A | VAL272 |
| A | TYR277 |
| A | ALA312 |
| A | SER329 |
| A | LYS330 |
| A | HOH543 |
| A | HOH621 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 410 |
| Chain | Residue |
| A | GLN140 |
| A | THR258 |
| A | HOH562 |
| A | HOH614 |
| A | HOH625 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 411 |
| Chain | Residue |
| A | SER297 |
| A | GLY301 |
| A | ILE302 |
| A | HOH526 |
| A | HOH586 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 412 |
| Chain | Residue |
| A | CYS255 |
| A | ASP279 |
| A | GLY281 |
| A | PRO282 |
| A | CYS290 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | ASP35 | |
| A | SER199 | |
