4KU3
Crystal Structure of C143S Xanthomonas Campestris OleA bound with myristic acid and myrisotoyl-CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0044550 | biological_process | secondary metabolite biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0044550 | biological_process | secondary metabolite biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PEG A 401 |
| Chain | Residue |
| A | LEU198 |
| A | HOH676 |
| A | HOH738 |
| A | ALA199 |
| A | THR248 |
| A | THR250 |
| A | VAL287 |
| A | SER288 |
| A | HIS291 |
| A | HOH616 |
| A | HOH633 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PEG A 402 |
| Chain | Residue |
| A | ASP35 |
| A | ARG73 |
| A | ILE309 |
| A | GLU312 |
| A | HIS313 |
| A | HOH658 |
| A | HOH705 |
| A | HOH717 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MYR B 401 |
| Chain | Residue |
| B | SER143 |
| B | LEU253 |
| B | GLY257 |
| B | ILE258 |
| B | ILE284 |
| B | HIS285 |
| B | HIS291 |
| B | ASN315 |
| B | LEU343 |
| B | ILE345 |
| B | GLY346 |
| B | SER347 |
| B | MYA402 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE MYA B 402 |
| Chain | Residue |
| B | THR60 |
| B | VAL66 |
| B | ALA67 |
| B | SER112 |
| B | GLU171 |
| B | THR172 |
| B | PHE194 |
| B | ARG195 |
| B | LEU198 |
| B | ALA199 |
| B | THR202 |
| B | CYS239 |
| B | ASN242 |
| B | THR250 |
| B | ARG251 |
| B | LEU253 |
| B | VAL287 |
| B | SER288 |
| B | PRO290 |
| B | GLY317 |
| B | MYR401 |
| B | HOH511 |
| B | HOH524 |
| B | HOH662 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"22524624","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27815501","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"29025976","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Acyl-thioester intermediate","evidences":[{"source":"PubMed","id":"22524624","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27815501","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"29025976","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22524624","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29025976","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"SEP-2017","submissionDatabase":"PDB data bank","title":"The role of OleA His285 in substrate coordination of long-chain acyl-CoA.","authors":["Jensen M.R.","Goblirsch B.R.","Esler M.A.","Christenson J.K.","Mohamed F.A.","Wackett L.P.","Wilmot C.M."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for activity","evidences":[{"source":"PubMed","id":"29430657","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
