4KS7

PAK6 kinase domain in complex with PF-3758309

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA A 701

Chain	Residue
A	LEU498
A	LYS626
A	HOH899

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site_id	AC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE X4Z A 702

Chain	Residue
A	PHE483
A	LEU484
A	GLN485
A	GLY487
A	ASP530
A	SER543
A	ASP544
A	HOH817
A	HOH961
A	HOH1020
A	GLY416
A	THR418
A	VAL421
A	LYS436
A	MET481
A	GLU482

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Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	24
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGEGSTGIVClArekhsgrq..........VAVK

Chain	Residue	Details
A	ILE413-LYS436

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159

Chain	Residue	Details
A	ASP526

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159

Chain	Residue	Details
A	ILE413
A	LYS436

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine; by autocatalysis => ECO:0000250

Chain	Residue	Details
A	SEP560

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