4KS3
Influenza Neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-[4-(3-hydroxypropyl)-1H-1,2,3-triazol-1-yl]-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004308 | molecular_function | exo-alpha-sialidase activity |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0016020 | cellular_component | membrane |
| A | 0033644 | cellular_component | host cell membrane |
| A | 0055036 | cellular_component | virion membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE 1SL A 501 |
| Chain | Residue |
| A | ARG118 |
| A | ARG224 |
| A | GLU276 |
| A | ARG371 |
| A | TYR406 |
| A | THR439 |
| A | HOH605 |
| A | GLU119 |
| A | THR148 |
| A | VAL149 |
| A | LYS150 |
| A | ASP151 |
| A | ARG152 |
| A | ARG156 |
| A | TRP178 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 502 |
| Chain | Residue |
| A | ASP293 |
| A | GLY297 |
| A | ASP324 |
| A | TYR347 |
| A | GLY348 |
