4KR9

Crystal structure of a 4-thiouridine synthetase - RNA complex at 3.5 Angstrom resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0002937	biological_process	tRNA 4-thiouridine biosynthesis
A	0003723	molecular_function	RNA binding
A	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0009228	biological_process	thiamine biosynthetic process
A	0009229	biological_process	thiamine diphosphate biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016783	molecular_function	sulfurtransferase activity
A	0034227	biological_process	tRNA thio-modification
A	0052837	biological_process	thiazole biosynthetic process
A	0140741	molecular_function	tRNA-uracil-4 sulfurtransferase activity
B	0000049	molecular_function	tRNA binding
B	0002937	biological_process	tRNA 4-thiouridine biosynthesis
B	0003723	molecular_function	RNA binding
B	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0009228	biological_process	thiamine biosynthetic process
B	0009229	biological_process	thiamine diphosphate biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016783	molecular_function	sulfurtransferase activity
B	0034227	biological_process	tRNA thio-modification
B	0052837	biological_process	thiazole biosynthetic process
B	0140741	molecular_function	tRNA-uracil-4 sulfurtransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00021

Chain	Residue	Details
A	LEU180
B	GLN295
A	THR205
A	ARG264
A	GLY286
A	GLN295
B	LEU180
B	THR205
B	ARG264
B	GLY286

---