4KMH

Crystal structure of Suppressor of Fused d20

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0003714	molecular_function	transcription corepressor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005929	cellular_component	cilium
A	0006355	biological_process	regulation of DNA-templated transcription
A	0007165	biological_process	signal transduction
A	0007286	biological_process	spermatid development
A	0008013	molecular_function	beta-catenin binding
A	0008134	molecular_function	transcription factor binding
A	0019901	molecular_function	protein kinase binding
A	0042308	biological_process	negative regulation of protein import into nucleus
A	0045668	biological_process	negative regulation of osteoblast differentiation
A	0045879	biological_process	negative regulation of smoothened signaling pathway
A	0097542	cellular_component	ciliary tip
A	0097546	cellular_component	ciliary base
A	0140311	molecular_function	protein sequestering activity
A	1990788	cellular_component	GLI-SUFU complex
A	2001040	biological_process	positive regulation of cellular response to drug
B	0000122	biological_process	negative regulation of transcription by RNA polymerase II
B	0003714	molecular_function	transcription corepressor activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005929	cellular_component	cilium
B	0006355	biological_process	regulation of DNA-templated transcription
B	0007165	biological_process	signal transduction
B	0007286	biological_process	spermatid development
B	0008013	molecular_function	beta-catenin binding
B	0008134	molecular_function	transcription factor binding
B	0019901	molecular_function	protein kinase binding
B	0042308	biological_process	negative regulation of protein import into nucleus
B	0045668	biological_process	negative regulation of osteoblast differentiation
B	0045879	biological_process	negative regulation of smoothened signaling pathway
B	0097542	cellular_component	ciliary tip
B	0097546	cellular_component	ciliary base
B	0140311	molecular_function	protein sequestering activity
B	1990788	cellular_component	GLI-SUFU complex
B	2001040	biological_process	positive regulation of cellular response to drug

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"27234298","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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