4KLN
Structure of p97 N-D1 A232E mutant in complex with ATPgS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0016887 | molecular_function | ATP hydrolysis activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0016887 | molecular_function | ATP hydrolysis activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE AGS A 800 |
| Chain | Residue |
| A | ASP205 |
| A | HIS384 |
| A | GLY408 |
| A | ALA409 |
| A | MG801 |
| A | HOH901 |
| A | HOH902 |
| A | HOH903 |
| B | ARG359 |
| B | PHE360 |
| A | GLY207 |
| A | GLY248 |
| A | THR249 |
| A | GLY250 |
| A | LYS251 |
| A | THR252 |
| A | LEU253 |
| A | ASN348 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 801 |
| Chain | Residue |
| A | THR252 |
| A | ASP304 |
| A | AGS800 |
| A | HOH901 |
| A | HOH902 |
| A | HOH903 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE AGS B 800 |
| Chain | Residue |
| B | ASP205 |
| B | GLY207 |
| B | GLY248 |
| B | THR249 |
| B | GLY250 |
| B | LYS251 |
| B | THR252 |
| B | LEU253 |
| B | ASN348 |
| B | HIS384 |
| B | GLY408 |
| B | ALA409 |
| B | MG801 |
| B | HOH901 |
| B | HOH902 |
| B | HOH903 |
| C | ARG359 |
| C | PHE360 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 801 |
| Chain | Residue |
| B | THR252 |
| B | AGS800 |
| B | HOH901 |
| B | HOH902 |
| B | HOH903 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE AGS C 800 |
| Chain | Residue |
| C | ASP205 |
| C | GLY207 |
| C | GLY248 |
| C | THR249 |
| C | GLY250 |
| C | LYS251 |
| C | THR252 |
| C | LEU253 |
| C | ASN348 |
| C | HIS384 |
| C | GLY408 |
| C | ALA409 |
| C | MG801 |
| C | HOH901 |
| C | HOH902 |
| C | HOH903 |
| C | HOH914 |
| D | ARG359 |
| D | PHE360 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 801 |
| Chain | Residue |
| C | THR252 |
| C | ASP304 |
| C | AGS800 |
| C | HOH901 |
| C | HOH902 |
| C | HOH903 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE AGS D 800 |
| Chain | Residue |
| D | ASP205 |
| D | ILE206 |
| D | GLY207 |
| D | GLY248 |
| D | THR249 |
| D | GLY250 |
| D | LYS251 |
| D | THR252 |
| D | LEU253 |
| D | ASN348 |
| D | HIS384 |
| D | GLY408 |
| D | ALA409 |
| D | MG801 |
| D | HOH901 |
| D | HOH902 |
| D | HOH903 |
| E | ARG359 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 801 |
| Chain | Residue |
| D | THR252 |
| D | ASP304 |
| D | AGS800 |
| D | HOH901 |
| D | HOH902 |
| D | HOH903 |
| site_id | AC9 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE AGS E 800 |
| Chain | Residue |
| E | THR249 |
| E | GLY250 |
| E | LYS251 |
| E | THR252 |
| E | LEU253 |
| E | ASN348 |
| E | HIS384 |
| E | GLY408 |
| E | ALA409 |
| E | MG801 |
| E | HOH901 |
| E | HOH902 |
| E | HOH903 |
| F | ARG359 |
| F | PHE360 |
| E | ASP205 |
| E | GLY207 |
| E | GLY248 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG E 801 |
| Chain | Residue |
| E | THR252 |
| E | ASP304 |
| E | AGS800 |
| E | HOH901 |
| E | HOH902 |
| E | HOH903 |
| site_id | BC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE AGS F 800 |
| Chain | Residue |
| A | ARG359 |
| A | PHE360 |
| F | ASP205 |
| F | GLY207 |
| F | GLY248 |
| F | THR249 |
| F | GLY250 |
| F | LYS251 |
| F | THR252 |
| F | LEU253 |
| F | ASN348 |
| F | HIS384 |
| F | GLY408 |
| F | ALA409 |
| F | MG801 |
| F | HOH901 |
| F | HOH902 |
| F | HOH903 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG F 801 |
| Chain | Residue |
| F | THR252 |
| F | ASP304 |
| F | AGS800 |
| F | HOH901 |
| F | HOH902 |
| F | HOH903 |
Functional Information from PROSITE/UniProt
| site_id | PS00674 |
| Number of Residues | 19 |
| Details | AAA AAA-protein family signature. ViVMaATNrpnsIDpALr.R |
| Chain | Residue | Details |
| A | VAL341-ARG359 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 48 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20512113","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"N6,N6,N6-trimethyllysine; by VCPKMT","evidences":[{"source":"PubMed","id":"22948820","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23349634","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
