4KH1
The R state structure of E. coli ATCase with CTP,UTP, and Magnesium bound
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0009347 | cellular_component | aspartate carbamoyltransferase complex |
| C | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| C | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0016597 | molecular_function | amino acid binding |
| C | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| D | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| D | 0009347 | cellular_component | aspartate carbamoyltransferase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PAL A 401 |
| Chain | Residue |
| A | SER52 |
| A | ARG229 |
| A | GLN231 |
| A | LEU267 |
| A | HOH510 |
| A | HOH532 |
| A | THR53 |
| A | ARG54 |
| A | THR55 |
| A | SER80 |
| A | LYS84 |
| A | ARG105 |
| A | HIS134 |
| A | ARG167 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 201 |
| Chain | Residue |
| B | CYS109 |
| B | CYS114 |
| B | CYS138 |
| B | CYS141 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CTP B 202 |
| Chain | Residue |
| B | ALA11 |
| B | ILE12 |
| B | VAL17 |
| B | ASP19 |
| B | HIS20 |
| B | LYS60 |
| B | ASN84 |
| B | TYR89 |
| B | VAL91 |
| B | LYS94 |
| B | UTP203 |
| B | MG204 |
| B | HOH301 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE UTP B 203 |
| Chain | Residue |
| B | LEU7 |
| B | GLN8 |
| B | VAL9 |
| B | HIS20 |
| B | PRO49 |
| B | SER50 |
| B | GLU52 |
| B | LYS56 |
| B | LEU58 |
| B | LYS60 |
| B | CTP202 |
| B | MG204 |
| B | HOH301 |
| B | HOH302 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 204 |
| Chain | Residue |
| B | CTP202 |
| B | UTP203 |
| B | HOH301 |
| B | HOH302 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 B 205 |
| Chain | Residue |
| B | ARG130 |
| B | GLU144 |
| B | SER146 |
| B | HOH320 |
| site_id | AC7 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PAL C 401 |
| Chain | Residue |
| C | SER52 |
| C | THR53 |
| C | ARG54 |
| C | THR55 |
| C | SER80 |
| C | LYS84 |
| C | ARG105 |
| C | HIS134 |
| C | ARG167 |
| C | THR168 |
| C | ARG229 |
| C | GLN231 |
| C | LEU267 |
| C | HOH503 |
| C | HOH507 |
| C | HOH649 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 201 |
| Chain | Residue |
| D | CYS109 |
| D | CYS114 |
| D | CYS138 |
| D | CYS141 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE CTP D 202 |
| Chain | Residue |
| D | ALA11 |
| D | ILE12 |
| D | VAL17 |
| D | ASP19 |
| D | HIS20 |
| D | LYS60 |
| D | ASN84 |
| D | ILE86 |
| D | TYR89 |
| D | VAL91 |
| D | LYS94 |
| D | UTP203 |
| D | MG204 |
| D | HOH301 |
| D | HOH302 |
| D | HOH323 |
| site_id | BC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE UTP D 203 |
| Chain | Residue |
| D | LYS60 |
| D | CTP202 |
| D | MG204 |
| D | HOH301 |
| D | HOH302 |
| D | LEU7 |
| D | GLN8 |
| D | VAL9 |
| D | HIS20 |
| D | PRO49 |
| D | SER50 |
| D | GLY51 |
| D | GLU52 |
| D | LYS56 |
| D | LEU58 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG D 204 |
| Chain | Residue |
| D | CTP202 |
| D | UTP203 |
| D | HOH301 |
| D | HOH302 |
Functional Information from PROSITE/UniProt
| site_id | PS00097 |
| Number of Residues | 8 |
| Details | CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FfEaSTRT |
| Chain | Residue | Details |
| A | PHE48-THR55 |
