Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4KER

Crystal structure of SsoPox W263V

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004063	molecular_function	aryldialkylphosphatase activity
A	0008270	molecular_function	zinc ion binding
A	0009056	biological_process	catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0046872	molecular_function	metal ion binding
B	0004063	molecular_function	aryldialkylphosphatase activity
B	0008270	molecular_function	zinc ion binding
B	0009056	biological_process	catabolic process
B	0016787	molecular_function	hydrolase activity
B	0016788	molecular_function	hydrolase activity, acting on ester bonds
B	0046872	molecular_function	metal ion binding
C	0004063	molecular_function	aryldialkylphosphatase activity
C	0008270	molecular_function	zinc ion binding
C	0009056	biological_process	catabolic process
C	0016787	molecular_function	hydrolase activity
C	0016788	molecular_function	hydrolase activity, acting on ester bonds
C	0046872	molecular_function	metal ion binding
D	0004063	molecular_function	aryldialkylphosphatase activity
D	0008270	molecular_function	zinc ion binding
D	0009056	biological_process	catabolic process
D	0016787	molecular_function	hydrolase activity
D	0016788	molecular_function	hydrolase activity, acting on ester bonds
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE2 A 401

Chain	Residue
A	HIS22
A	HIS24
A	KCX137
A	ASP256
A	CO402
A	HOH599

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CO A 402

Chain	Residue
A	ARG223
A	FE2401
A	HOH599
A	KCX137
A	HIS170
A	HIS199

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 403

Chain	Residue
A	SER171
A	ASN172
A	ALA173
A	ASP202
A	PHE229
A	HOH544

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 404

Chain	Residue
A	ASN160
A	LYS164
A	GLY189
A	ASP191
A	HOH579

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 405

Chain	Residue
A	HIS120
A	GLY125
A	GLY128
A	THR129
A	LEU130
C	LYS164

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PEG A 406

Chain	Residue
A	ASP256
A	CYS258
A	HOH599

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE2 B 401

Chain	Residue
B	HIS22
B	HIS24
B	KCX137
B	ASP256
B	CO402
B	GOL406
B	HOH539

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CO B 402

Chain	Residue
B	KCX137
B	HIS170
B	HIS199
B	FE2401
B	GOL406
B	HOH539

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO B 403

Chain	Residue
B	LEU25
B	ARG26
B	ASP66
B	THR68
B	GLY73
B	ASP75

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 404

Chain	Residue
B	ASN172
B	ALA173
B	ASP202
B	HOH561

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 405

Chain	Residue
B	ASN160
B	LYS164
B	GLY189
B	ASP191

site_id	BC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL B 406

Chain	Residue
B	HIS24
B	TYR97
B	KCX137
B	HIS170
B	ARG223
B	ASP256
B	CYS258
B	FE2401
B	CO402
B	HOH539

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 407

Chain	Residue
B	HIS120
B	GLY128
B	THR129
B	HOH532

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE2 C 401

Chain	Residue
C	HIS22
C	HIS24
C	KCX137
C	ASP256
C	CO402
C	HOH583

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CO C 402

Chain	Residue
C	KCX137
C	HIS170
C	HIS199
C	ARG223
C	FE2401
C	GOL404
C	HOH583

site_id	BC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO C 403

Chain	Residue
C	SER171
C	ASN172
C	ALA173
C	HIS174
C	ASP202
C	PHE229
C	HOH515

site_id	BC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL C 404

Chain	Residue
C	HOH583
C	ARG223
C	ASP256
C	CYS258
C	ILE261
C	CO402
C	EDO407

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL C 405

Chain	Residue
A	ARG77
C	ASN160
C	LYS164
C	GLY189
C	VAL190
C	ASP191

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO C 406

Chain	Residue
C	HOH519
C	HOH525

site_id	CC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO C 407

Chain	Residue
C	THR265
C	ALA266
C	GOL404

site_id	CC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE2 D 401

Chain	Residue
D	HIS22
D	HIS24
D	KCX137
D	ASP256
D	CO402
D	HOH586

site_id	CC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CO D 402

Chain	Residue
D	KCX137
D	HIS170
D	HIS199
D	FE2401
D	HOH586
D	HOH588

site_id	CC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO D 403

Chain	Residue
D	SER171
D	ALA173
D	HIS174
D	ASP202
D	PHE229
D	HOH507
D	HOH549

site_id	CC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL D 404

Chain	Residue
D	PRO4
D	LEU5
D	LYS8
D	ASP9
D	SER10
D	LEU130
D	ASN131
D	LYS132

site_id	CC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL D 405

Chain	Residue
D	ASN160
D	LYS164
D	GLY189
D	ASP191
D	LYS194

site_id	CC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO D 406

Chain	Residue
D	GLY128
D	THR129
D	HOH508

Functional Information from PROSITE/UniProt

site_id	PS01322
Number of Residues	9
Details	PHOSPHOTRIESTERASE_1 Phosphotriesterase family signature 1. GfTLiHEHL

Chain	Residue	Details
A	GLY17-LEU25

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18486146","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2VC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VC7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UF9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KER","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KF1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"description":"via carbamate group","evidences":[{"source":"PubMed","id":"18486146","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2VC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VC7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UF9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KER","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KF1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"N6-carboxylysine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00679","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18486146","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2VC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VC7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UF9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KER","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KF1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)