4KDY
Crystal structure of maleylacetoacetate isomerase from Anaeromyxobacter dehalogenans 2CP-1, Target EFI-507175, with bound GSH in the active site
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006559 | biological_process | L-phenylalanine catabolic process |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0009072 | biological_process | aromatic amino acid metabolic process |
| A | 0016034 | molecular_function | maleylacetoacetate isomerase activity |
| A | 0016853 | molecular_function | isomerase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006559 | biological_process | L-phenylalanine catabolic process |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0009072 | biological_process | aromatic amino acid metabolic process |
| B | 0016034 | molecular_function | maleylacetoacetate isomerase activity |
| B | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GSH A 301 |
| Chain | Residue |
| A | SER13 |
| A | LEU116 |
| A | HOH411 |
| A | HOH445 |
| A | HOH513 |
| B | SER107 |
| B | ARG139 |
| B | HOH552 |
| A | ARG16 |
| A | VAL54 |
| A | PRO55 |
| A | GLN70 |
| A | SER71 |
| A | ASN106 |
| A | GLN110 |
| A | ASN114 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CIT A 302 |
| Chain | Residue |
| A | TYR8 |
| A | ARG10 |
| A | GLU39 |
| A | ALA115 |
| A | ARG177 |
| A | HOH446 |
| A | HOH515 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 303 |
| Chain | Residue |
| A | HIS104 |
| A | GLY108 |
| A | ARG139 |
| A | HOH486 |
| B | GLN53 |
| B | GLN70 |
| site_id | AC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE GSH B 301 |
| Chain | Residue |
| A | SER107 |
| A | HOH484 |
| B | SER11 |
| B | SER13 |
| B | ARG16 |
| B | LEU35 |
| B | GLN38 |
| B | GLU39 |
| B | GLN42 |
| B | SER52 |
| B | GLN53 |
| B | VAL54 |
| B | PRO55 |
| B | GLN70 |
| B | SER71 |
| B | ASN106 |
| B | ASN114 |
| B | HOH420 |
| B | HOH532 |
| B | HOH539 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 302 |
| Chain | Residue |
| A | ALA96 |
| A | ARG97 |
| A | ALA100 |
| B | LEU67 |
| B | LEU68 |
| B | VAL69 |
| B | ALA73 |
| B | HOH553 |
