Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM A 801 |
| Chain | Residue |
| A | TRP409 |
| A | TYR706 |
| A | H4B802 |
| A | 5H3805 |
| A | HOH917 |
| A | HOH937 |
| A | HOH939 |
| A | HOH953 |
| A | HOH1021 |
| A | ARG414 |
| A | CYS415 |
| A | SER457 |
| A | PHE584 |
| A | SER585 |
| A | TRP587 |
| A | GLU592 |
| A | TRP678 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE H4B A 802 |
| Chain | Residue |
| A | SER334 |
| A | ARG596 |
| A | VAL677 |
| A | TRP678 |
| A | HEM801 |
| A | HOH911 |
| A | HOH917 |
| A | HOH924 |
| A | HOH1059 |
| B | TRP676 |
| B | PHE691 |
| B | HIS692 |
| B | GLN693 |
| B | GLU694 |
| B | HOH1086 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 803 |
| Chain | Residue |
| A | GLY417 |
| A | GLN420 |
| A | TRP587 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE MTL A 804 |
| Chain | Residue |
| A | ARG481 |
| A | GLU592 |
| A | ARG596 |
| A | ASP597 |
| A | ASP600 |
| A | ARG603 |
| A | 5H3805 |
| A | HOH909 |
| A | HOH917 |
| A | HOH977 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 5H3 A 805 |
| Chain | Residue |
| A | PRO565 |
| A | VAL567 |
| A | PHE584 |
| A | SER585 |
| A | GLY586 |
| A | TRP587 |
| A | GLU592 |
| A | HEM801 |
| A | MTL804 |
| A | HOH953 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 806 |
| Chain | Residue |
| A | CYS326 |
| A | CYS331 |
| B | CYS326 |
| B | CYS331 |
| site_id | AC7 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HEM B 801 |
| Chain | Residue |
| B | TRP409 |
| B | ARG414 |
| B | CYS415 |
| B | SER457 |
| B | PHE584 |
| B | SER585 |
| B | TRP587 |
| B | GLU592 |
| B | TRP678 |
| B | TYR706 |
| B | H4B802 |
| B | 5H3803 |
| B | EDO807 |
| B | HOH940 |
| B | HOH954 |
| B | HOH1080 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE H4B B 802 |
| Chain | Residue |
| A | TRP676 |
| A | PHE691 |
| A | HIS692 |
| A | GLN693 |
| A | GLU694 |
| B | SER334 |
| B | MET336 |
| B | ARG596 |
| B | VAL677 |
| B | TRP678 |
| B | HEM801 |
| B | HOH922 |
| B | HOH940 |
| B | HOH977 |
| B | HOH1026 |
| site_id | AC9 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 5H3 B 803 |
| Chain | Residue |
| B | MTL805 |
| B | MTL806 |
| B | EDO807 |
| B | HOH1026 |
| B | MET336 |
| B | PRO565 |
| B | VAL567 |
| B | PHE584 |
| B | SER585 |
| B | GLY586 |
| B | TRP587 |
| B | GLU592 |
| B | HEM801 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT B 804 |
| Chain | Residue |
| B | GLY417 |
| B | GLN420 |
| B | TRP587 |
| B | VAL649 |
| B | HOH1024 |
| B | HOH1104 |
| B | HOH1105 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE MTL B 805 |
| Chain | Residue |
| B | ARG481 |
| B | GLU592 |
| B | ARG596 |
| B | ASP597 |
| B | ASP600 |
| B | ARG603 |
| B | 5H3803 |
| B | HOH914 |
| B | HOH940 |
| site_id | BC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MTL B 806 |
| Chain | Residue |
| B | SER477 |
| B | ALA497 |
| B | ASN498 |
| B | GLN500 |
| B | PHE501 |
| B | ASN569 |
| B | ASP709 |
| B | 5H3803 |
| B | EDO807 |
| B | HOH913 |
| B | HOH1003 |
| B | HOH1037 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 807 |
| Chain | Residue |
| B | ASN569 |
| B | MET570 |
| B | HEM801 |
| B | 5H3803 |
| B | MTL806 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG414-TRP421 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P29475","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"UniProtKB","id":"P29475","evidenceCode":"ECO:0000250"}]} |
