4KAM
X-ray crystal structure of O-acetylhomoserine sulfhydrylase MetC from Mycobacterium marinum ATCC BAA-535 / M
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0009086 | biological_process | methionine biosynthetic process |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0019346 | biological_process | transsulfuration |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0009086 | biological_process | methionine biosynthetic process |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0019346 | biological_process | transsulfuration |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0009086 | biological_process | methionine biosynthetic process |
| C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| C | 0019346 | biological_process | transsulfuration |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0006520 | biological_process | amino acid metabolic process |
| D | 0009086 | biological_process | methionine biosynthetic process |
| D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| D | 0019346 | biological_process | transsulfuration |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | SER96 |
| A | GLY97 |
| A | GLN98 |
| A | SER217 |
| A | THR219 |
| A | LYS220 |
| A | HOH704 |
| A | HOH705 |
| A | HOH707 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 502 |
| Chain | Residue |
| A | TYR122 |
| A | GLY123 |
| A | ARG414 |
| A | HOH815 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 501 |
| Chain | Residue |
| B | SER96 |
| B | GLY97 |
| B | GLN98 |
| B | SER217 |
| B | THR219 |
| B | LYS220 |
| B | ALA230 |
| B | HOH658 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 502 |
| Chain | Residue |
| B | TYR122 |
| B | GLY123 |
| B | ARG414 |
| B | HOH663 |
| B | HOH700 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 C 501 |
| Chain | Residue |
| C | SER96 |
| C | GLY97 |
| C | GLN98 |
| C | SER217 |
| C | THR219 |
| C | LYS220 |
| C | HOH696 |
| C | HOH705 |
| C | HOH824 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 502 |
| Chain | Residue |
| C | TYR122 |
| C | GLY123 |
| C | ARG414 |
| C | HOH789 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 501 |
| Chain | Residue |
| D | SER96 |
| D | GLY97 |
| D | GLN98 |
| D | SER217 |
| D | THR219 |
| D | HOH626 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 502 |
| Chain | Residue |
| D | TYR122 |
| D | GLY123 |
| D | ARG414 |
Functional Information from PROSITE/UniProt
| site_id | PS00868 |
| Number of Residues | 15 |
| Details | CYS_MET_METAB_PP Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. DIvvhSATKYLgGHG |
| Chain | Residue | Details |
| A | ASP212-GLY226 |
