4K7I

HUMAN PEROXIREDOXIN 5 with a fragment

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008379	molecular_function	thioredoxin peroxidase activity
A	0016491	molecular_function	oxidoreductase activity
A	0034599	biological_process	cellular response to oxidative stress
B	0008379	molecular_function	thioredoxin peroxidase activity
B	0016491	molecular_function	oxidoreductase activity
B	0034599	biological_process	cellular response to oxidative stress
C	0008379	molecular_function	thioredoxin peroxidase activity
C	0016491	molecular_function	oxidoreductase activity
C	0034599	biological_process	cellular response to oxidative stress

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CAQ A 201

Chain	Residue
A	PRO40
A	THR44
A	PRO45
A	GLY46
A	CYS47
A	ARG127
A	HOH2106
C	ALA64

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE DMS A 202

Chain	Residue
A	SER48
A	GLU83
A	TRP84
A	HIS88
A	PHE43

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CAQ B 201

Chain	Residue
A	ALA64
B	PRO40
B	THR44
B	PRO45
B	GLY46
B	CYS47
B	ARG127

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DMS B 202

Chain	Residue
B	VAL70
B	GLY92
B	LYS93
B	ARG95

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: Cysteine sulfenic acid (-SOH) intermediate => ECO:0000305|PubMed:10751410, ECO:0000305|PubMed:20643143

Chain	Residue	Details
A	CYS47
B	CYS47
C	CYS47

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P99029

Chain	Residue	Details
A	LYS22
B	LYS22
C	LYS22

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P99029

Chain	Residue	Details
A	LYS30
B	LYS30
C	LYS30

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P99029

Chain	Residue	Details
A	LYS63
B	LYS63
C	LYS63

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9R063

Chain	Residue	Details
A	SER118
B	SER118
C	SER118

---

site_id	SWS_FT_FI6
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P99029

Chain	Residue	Details
A	SER129
B	SER129
C	SER129

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	LIPID: S-palmitoyl cysteine => ECO:0000269|PubMed:31740833

Chain	Residue	Details
A	CYS47
B	CYS47
C	CYS47

---