4K3S

E. coli sliding clamp in P1 crystal space group

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006271	biological_process	DNA strand elongation involved in DNA replication
A	0006974	biological_process	DNA damage response
A	0008408	molecular_function	3'-5' exonuclease activity
A	0009360	cellular_component	DNA polymerase III complex
A	0030174	biological_process	regulation of DNA-templated DNA replication initiation
A	0030894	cellular_component	replisome
A	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
A	0042276	biological_process	error-prone translesion synthesis
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0044787	biological_process	bacterial-type DNA replication
A	1990078	cellular_component	replication inhibiting complex
A	1990085	cellular_component	Hda-beta clamp complex
B	0003677	molecular_function	DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006271	biological_process	DNA strand elongation involved in DNA replication
B	0006974	biological_process	DNA damage response
B	0008408	molecular_function	3'-5' exonuclease activity
B	0009360	cellular_component	DNA polymerase III complex
B	0030174	biological_process	regulation of DNA-templated DNA replication initiation
B	0030894	cellular_component	replisome
B	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
B	0042276	biological_process	error-prone translesion synthesis
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0044787	biological_process	bacterial-type DNA replication
B	1990078	cellular_component	replication inhibiting complex
B	1990085	cellular_component	Hda-beta clamp complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 401

Chain	Residue
A	GLU6
A	GLY85
A	GLU87
B	ASP120

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PG4 B 401

Chain	Residue
B	SER18
B	GLY22
B	ARG73
B	PHE76
B	ARG80

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site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE P4C B 402

Chain	Residue
A	VAL151
A	ARG152
A	GLN265
B	ARG7
B	LEU11
B	GLN15
B	ARG80
B	LEU82
B	GLU84
B	HOH547

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000305|PubMed:18191219

Chain	Residue	Details
A	ARG24
A	GLN149
A	TYR153
B	ARG24
B	GLN149
B	TYR153

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:18191219

Chain	Residue	Details
A	ARG73
B	ARG73

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