4K3O
E. coli sliding clamp in complex with AcQADLF
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006260 | biological_process | DNA replication |
| A | 0006261 | biological_process | DNA-templated DNA replication |
| A | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| A | 0009360 | cellular_component | DNA polymerase III complex |
| A | 0030174 | biological_process | regulation of DNA-templated DNA replication initiation |
| A | 0030894 | cellular_component | replisome |
| A | 0032297 | biological_process | negative regulation of DNA-templated DNA replication initiation |
| A | 0042276 | biological_process | error-prone translesion synthesis |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0044787 | biological_process | bacterial-type DNA replication |
| A | 1990078 | cellular_component | replication inhibiting complex |
| A | 1990085 | cellular_component | Hda-beta clamp complex |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006260 | biological_process | DNA replication |
| B | 0006261 | biological_process | DNA-templated DNA replication |
| B | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008408 | molecular_function | 3'-5' exonuclease activity |
| B | 0009360 | cellular_component | DNA polymerase III complex |
| B | 0030174 | biological_process | regulation of DNA-templated DNA replication initiation |
| B | 0030894 | cellular_component | replisome |
| B | 0032297 | biological_process | negative regulation of DNA-templated DNA replication initiation |
| B | 0042276 | biological_process | error-prone translesion synthesis |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0044787 | biological_process | bacterial-type DNA replication |
| B | 1990078 | cellular_component | replication inhibiting complex |
| B | 1990085 | cellular_component | Hda-beta clamp complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 401 |
| Chain | Residue |
| A | ASP121 |
| A | TRP122 |
| A | ARG224 |
| A | HOH771 |
| B | ALA38 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CA A 402 |
| Chain | Residue |
| A | HOH637 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA A 403 |
| Chain | Residue |
| A | VAL151 |
| A | TYR153 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 404 |
| Chain | Residue |
| A | ALA67 |
| A | HOH609 |
| B | GLU125 |
| A | GLY66 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 405 |
| Chain | Residue |
| A | GLY280 |
| A | ALA294 |
| A | ASN295 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PGE A 406 |
| Chain | Residue |
| A | HIS9 |
| A | ARG56 |
| A | VAL57 |
| A | ALA58 |
| A | ASP229 |
| A | HOH581 |
| A | HOH648 |
| A | HOH737 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 407 |
| Chain | Residue |
| A | SER181 |
| A | SER356 |
| A | HOH780 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO A 408 |
| Chain | Residue |
| A | LYS291 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG B 401 |
| Chain | Residue |
| A | LYS250 |
| A | THR341 |
| A | SER345 |
| A | HOH529 |
| A | HOH735 |
| A | HOH744 |
| B | GLU163 |
| B | GLU166 |
| B | HOH716 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG B 402 |
| Chain | Residue |
| B | THR41 |
| B | ARG56 |
| B | PGE407 |
| B | HOH576 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 403 |
| Chain | Residue |
| B | ASN118 |
| B | LEU119 |
| B | HOH728 |
| B | HOH785 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 404 |
| Chain | Residue |
| B | GLU161 |
| B | THR162 |
| B | GLU163 |
| B | SER190 |
| B | HIS191 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA B 405 |
| Chain | Residue |
| B | HOH619 |
| B | HOH666 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PG4 B 406 |
| Chain | Residue |
| A | ALA38 |
| A | HOH512 |
| A | HOH644 |
| B | ASP121 |
| B | TRP122 |
| B | SER124 |
| B | GLN217 |
| B | ARG224 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PGE B 407 |
| Chain | Residue |
| B | HIS9 |
| B | THR41 |
| B | ARG56 |
| B | VAL57 |
| B | ALA58 |
| B | ASP229 |
| B | PEG402 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 408 |
| Chain | Residue |
| B | GLN16 |
| B | GLU202 |
| B | ARG205 |
| B | MET206 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PGE B 409 |
| Chain | Residue |
| B | TYR284 |
| B | LYS291 |
| B | HOH714 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG B 410 |
| Chain | Residue |
| A | ASP77 |
| B | ALA271 |
| B | ILE272 |
| B | SER274 |
| B | GLU276 |
| B | ARG279 |
| B | HOH702 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 228 |
| Details | Region: {"description":"2","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 240 |
| Details | Region: {"description":"3","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18191219","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18191219","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
