4K3L
E. coli sliding clamp in complex with AcLF dipeptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006260 | biological_process | DNA replication |
| A | 0006261 | biological_process | DNA-templated DNA replication |
| A | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| A | 0009360 | cellular_component | DNA polymerase III complex |
| A | 0030174 | biological_process | regulation of DNA-templated DNA replication initiation |
| A | 0030894 | cellular_component | replisome |
| A | 0032297 | biological_process | negative regulation of DNA-templated DNA replication initiation |
| A | 0042276 | biological_process | error-prone translesion synthesis |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0044787 | biological_process | bacterial-type DNA replication |
| A | 1990078 | cellular_component | replication inhibiting complex |
| A | 1990085 | cellular_component | Hda-beta clamp complex |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006260 | biological_process | DNA replication |
| B | 0006261 | biological_process | DNA-templated DNA replication |
| B | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008408 | molecular_function | 3'-5' exonuclease activity |
| B | 0009360 | cellular_component | DNA polymerase III complex |
| B | 0030174 | biological_process | regulation of DNA-templated DNA replication initiation |
| B | 0030894 | cellular_component | replisome |
| B | 0032297 | biological_process | negative regulation of DNA-templated DNA replication initiation |
| B | 0042276 | biological_process | error-prone translesion synthesis |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0044787 | biological_process | bacterial-type DNA replication |
| B | 1990078 | cellular_component | replication inhibiting complex |
| B | 1990085 | cellular_component | Hda-beta clamp complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 403 |
| Chain | Residue |
| A | GLU6 |
| A | HIS9 |
| A | GLN61 |
| A | HOH560 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 404 |
| Chain | Residue |
| A | SER181 |
| A | GLN355 |
| A | SER356 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 405 |
| Chain | Residue |
| A | ASN295 |
| A | ASN296 |
| A | PRO297 |
| A | HOH535 |
| A | ASN275 |
| A | ARG282 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 406 |
| Chain | Residue |
| A | ASP121 |
| A | TRP122 |
| A | ARG224 |
| A | HOH828 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 408 |
| Chain | Residue |
| A | HOH618 |
| A | HOH859 |
| B | MET1 |
| B | LYS2 |
| B | GLU64 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 403 |
| Chain | Residue |
| A | HOH534 |
| B | GLU163 |
| B | GLU166 |
| B | HOH588 |
| B | HOH617 |
| B | HOH792 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 404 |
| Chain | Residue |
| B | PRO249 |
| B | PRO252 |
| B | MET339 |
| B | LEU340 |
| B | THR341 |
| B | SER346 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA B 406 |
| Chain | Residue |
| B | GLY46 |
| B | GLU202 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG B 407 |
| Chain | Residue |
| B | ASP121 |
| B | TRP122 |
| B | ARG224 |
| B | HOH651 |
| B | HOH836 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG B 408 |
| Chain | Residue |
| B | ALA133 |
| B | HOH868 |
| site_id | BC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PGE B 409 |
| Chain | Residue |
| B | GLN132 |
| B | MET206 |
| B | ASP208 |
| B | GLY210 |
| B | ASP211 |
| B | ASN212 |
| B | VAL227 |
| B | PHE230 |
| B | HOH615 |
| B | HOH805 |
| B | HOH806 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG B 410 |
| Chain | Residue |
| B | SER187 |
| B | LEU188 |
| B | PRO189 |
| B | HOH786 |
| B | HOH818 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 412 |
| Chain | Residue |
| A | PRO65 |
| B | VAL126 |
| B | GLU127 |
| B | HOH616 |
| B | HOH790 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA B 413 |
| Chain | Residue |
| B | PRO83 |
| B | HOH656 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 414 |
| Chain | Residue |
| B | GLU161 |
| B | GLU163 |
| B | ARG168 |
| B | ASP243 |
| B | TYR244 |
| B | ARG245 |
| B | HOH648 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 416 |
| Chain | Residue |
| B | GLU95 |
| B | THR110 |
| B | HOH688 |
| B | HOH817 |
| B | HOH822 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 417 |
| Chain | Residue |
| A | HOH724 |
| A | HOH758 |
| B | HOH685 |
| B | HOH691 |
| B | HOH767 |
| B | HOH899 |
| site_id | BC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR LINKED RESIDUES A 400 to 402 |
| Chain | Residue |
| A | ARG152 |
| A | THR172 |
| A | GLY174 |
| A | ARG176 |
| A | PRO242 |
| A | MET362 |
| A | HOH563 |
| A | HOH611 |
| A | HOH652 |
| B | ASN251 |
| site_id | CC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR LINKED RESIDUES B 400 to 402 |
| Chain | Residue |
| B | MET362 |
| B | HOH599 |
| B | HOH759 |
| B | THR172 |
| B | GLY174 |
| B | HIS175 |
| B | ARG176 |
| B | PRO242 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:18191219 |
| Chain | Residue | Details |
| A | ARG24 | |
| A | GLN149 | |
| A | TYR153 | |
| B | ARG24 | |
| B | GLN149 | |
| B | TYR153 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:18191219 |
| Chain | Residue | Details |
| A | ARG73 | |
| B | ARG73 |
