4K3K
E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006260 | biological_process | DNA replication |
| A | 0006261 | biological_process | DNA-templated DNA replication |
| A | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| A | 0009360 | cellular_component | DNA polymerase III complex |
| A | 0030174 | biological_process | regulation of DNA-templated DNA replication initiation |
| A | 0030894 | cellular_component | replisome |
| A | 0032297 | biological_process | negative regulation of DNA-templated DNA replication initiation |
| A | 0042276 | biological_process | error-prone translesion synthesis |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0044787 | biological_process | bacterial-type DNA replication |
| A | 1990078 | cellular_component | replication inhibiting complex |
| A | 1990085 | cellular_component | Hda-beta clamp complex |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006260 | biological_process | DNA replication |
| B | 0006261 | biological_process | DNA-templated DNA replication |
| B | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008408 | molecular_function | 3'-5' exonuclease activity |
| B | 0009360 | cellular_component | DNA polymerase III complex |
| B | 0030174 | biological_process | regulation of DNA-templated DNA replication initiation |
| B | 0030894 | cellular_component | replisome |
| B | 0032297 | biological_process | negative regulation of DNA-templated DNA replication initiation |
| B | 0042276 | biological_process | error-prone translesion synthesis |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0044787 | biological_process | bacterial-type DNA replication |
| B | 1990078 | cellular_component | replication inhibiting complex |
| B | 1990085 | cellular_component | Hda-beta clamp complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 401 |
| Chain | Residue |
| A | GLU6 |
| A | GLN61 |
| A | HOH685 |
| B | HOH596 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 402 |
| Chain | Residue |
| A | GLU161 |
| A | HOH642 |
| A | HOH798 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA A 403 |
| Chain | Residue |
| A | GLY46 |
| A | HOH723 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PG4 A 404 |
| Chain | Residue |
| A | SER181 |
| A | GLN355 |
| A | HOH760 |
| B | ARG365 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PG4 A 405 |
| Chain | Residue |
| A | GLN123 |
| A | SER124 |
| A | GLN217 |
| A | HOH669 |
| B | GLN36 |
| B | VAL37 |
| B | ALA38 |
| B | ASP39 |
| B | GLY66 |
| B | HOH604 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG A 406 |
| Chain | Residue |
| A | MET1 |
| A | PRO65 |
| A | GLY66 |
| A | ALA67 |
| A | LEU92 |
| B | GLN123 |
| B | GLU125 |
| B | HOH581 |
| B | HOH668 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SFK A 407 |
| Chain | Residue |
| A | THR172 |
| A | GLY174 |
| A | HIS175 |
| A | ARG176 |
| A | PRO242 |
| A | MET362 |
| A | HOH552 |
| A | HOH557 |
| A | HOH573 |
| A | HOH590 |
| A | HOH601 |
| A | HOH738 |
| B | HOH560 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 401 |
| Chain | Residue |
| A | HOH572 |
| B | GLU6 |
| B | GLY85 |
| B | GLU87 |
| B | HOH804 |
| B | HOH805 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PG4 B 402 |
| Chain | Residue |
| B | SER18 |
| B | LEU21 |
| B | ARG73 |
| B | PHE76 |
| B | ARG80 |
| B | HOH632 |
| B | HOH798 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PG4 B 403 |
| Chain | Residue |
| A | VAL151 |
| A | ARG152 |
| A | GLN265 |
| B | ARG7 |
| B | ARG80 |
| B | GLY81 |
| B | LEU82 |
| B | HOH589 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 404 |
| Chain | Residue |
| A | HOH550 |
| B | VAL5 |
| B | GLU6 |
| B | HIS9 |
| B | GLN61 |
| B | HOH520 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:18191219 |
| Chain | Residue | Details |
| A | ARG24 | |
| A | GLN149 | |
| A | TYR153 | |
| B | ARG24 | |
| B | GLN149 | |
| B | TYR153 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:18191219 |
| Chain | Residue | Details |
| A | ARG73 | |
| B | ARG73 |
