4K39
Native anSMEcpe with bound AdoMet and Cp18Cys peptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SF4 A 501 |
| Chain | Residue |
| A | CYS255 |
| A | GLY256 |
| A | CYS261 |
| A | THR262 |
| A | GLN264 |
| A | CYS276 |
| A | CYS330 |
| A | ARG332 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SF4 A 502 |
| Chain | Residue |
| A | CYS320 |
| A | CYS326 |
| A | CYS348 |
| A | LYS352 |
| A | CYS317 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SF4 A 503 |
| Chain | Residue |
| A | CYS15 |
| A | CYS19 |
| A | CYS22 |
| A | GLY66 |
| A | ASN100 |
| A | ARG134 |
| A | SAM504 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE SAM A 504 |
| Chain | Residue |
| A | TYR21 |
| A | PHE23 |
| A | GLY65 |
| A | GLY66 |
| A | GLU67 |
| A | GLN98 |
| A | THR99 |
| A | ASN100 |
| A | SER122 |
| A | ARG134 |
| A | LEU163 |
| A | VAL165 |
| A | ILE192 |
| A | ASN193 |
| A | CYS194 |
| A | LEU195 |
| A | SF4503 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 505 |
| Chain | Residue |
| A | ALA171 |
| A | ARG172 |
| A | HIS173 |
| A | VAL174 |
| A | ASN175 |
| A | ASN220 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 506 |
| Chain | Residue |
| A | MET292 |
| A | GLU296 |
| A | THR300 |
| A | HOH771 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SF4 B 501 |
| Chain | Residue |
| B | CYS255 |
| B | GLY256 |
| B | CYS261 |
| B | THR262 |
| B | CYS276 |
| B | CYS330 |
| B | ARG332 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SF4 B 502 |
| Chain | Residue |
| B | GLU316 |
| B | CYS317 |
| B | CYS320 |
| B | CYS326 |
| B | CYS348 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SF4 B 503 |
| Chain | Residue |
| B | CYS15 |
| B | LEU17 |
| B | CYS19 |
| B | CYS22 |
| B | HIS25 |
| B | ARG134 |
| B | HOH808 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 504 |
| Chain | Residue |
| B | PHE191 |
| B | TYR239 |
| B | HOH663 |
| B | HOH724 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 505 |
| Chain | Residue |
| B | TYR21 |
| B | ILE192 |
| site_id | BC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR CHAIN C OF CP18CYS PEPTIDE |
| Chain | Residue |
| A | GLN64 |
| A | SER96 |
| A | LEU118 |
| A | GLY120 |
| A | GLU159 |
| A | PHE160 |
| A | ASN161 |
| A | LEU163 |
| A | PHE188 |
| A | GLN190 |
| A | ILE192 |
| A | ARG238 |
| A | SER253 |
| A | SER254 |
| A | CYS255 |
| A | GLN264 |
| A | ASP277 |
| A | HOH765 |
| A | HOH850 |
| C | HOH101 |
| C | HOH102 |
| site_id | BC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR CHAIN D OF CP18CYS PEPTIDE |
| Chain | Residue |
| B | ASN161 |
| B | PHE188 |
| B | GLN190 |
| B | ILE192 |
| B | GLU201 |
| B | GLU245 |
| B | SER253 |
| B | SER254 |
| B | CYS255 |
| B | GLN264 |
| B | ASP277 |
| B | HOH635 |
| B | HOH701 |
| D | HOH102 |
| D | HOH103 |
| D | HOH105 |
| B | ALA62 |
| B | SER96 |
| B | LEU118 |
| B | GLY120 |
| B | GLU159 |
| B | PHE160 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"23650368","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 32 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23650368","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4K36","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K37","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K38","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K39","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
